Skip to content

Commit 7e74146

Browse files
authored
Update index.md
1 parent e0fe2bd commit 7e74146

1 file changed

Lines changed: 1 addition & 1 deletion

File tree

Research/index.md

Lines changed: 1 addition & 1 deletion
Original file line numberDiff line numberDiff line change
@@ -16,7 +16,7 @@ Using the above neuro-behavioral recording platform, we are working towards reco
1616
### miniSTIM
1717
Great technological advances over the past decades have allowed researchers to begin to optically measure and modulate neural activity but these approaches are often limited to head-fix animals when studying neural function at spatial and temporal scales relevant to internal neural circuit dynamics. While a great deal of scientific and technological progress has been made, there is still much to learn concerning complex neural function, especially within the context of natural behavior. This gap in knowledge, at least in part, is due to a lack of accessible tools for simultaneously modulating and observing large-scale neural circuits with single cell precision in freely behaving animals. This project will fill this gap by developing open-source, head-mounted miniature microscopes with spatiotemporal illumination capabilities for both patterned photo-stimulation and improved neural imaging in freely behaving animals. To maximize the impact of our efforts, all tools and technologies developed for this project will be open-source and shared widely with the scientific community through online resources and technical workshops.
1818

19-
### Spatio-Temporal Illumination Miniscope (STIMscope)
19+
### Spatio-Temporal Illumination Microscope (STIMscope)
2020
The study of neural dynamics, characterized by intricate spatial and temporal patterns, demands innovative approaches for comprehensive investigation. To address this need, we developed a novel, real-time closed-loop platform called the Spatio-Temporal Illumination Microscope (STIMscope). This system provides cellular-resolution, large field-of-view imaging and patterned stimulation in an open-source, customizable, and cost-effective package. A real-time synchronized control system enables seamless communication between all components, while custom firmware and a GPU-accelerated analysis pipeline ensure precise control and coordination. STIMscope’s versatile design supports a wide range of applications in neural imaging and neuromodulation, including studies in head-fixed mice and research in cell or tissue culture models.
2121

2222
### Place cell dynamics across techniques and animal species

0 commit comments

Comments
 (0)