Dear developers,
Thank you for your useful tools.
I am currently working on a dataset where cell types are hard to define, thus we don't know if there are any progenitors.
I use the 5 scores (ESC+iPSC, EB, ED, ECTO, MESO) to see any correlations between those.
Something I cannot wrap my head around is why some scores are highly negatively correlated (e.g Embryoid bodies and ESC+iPSC, correlation=-0.9) in different samples. Because of their nature (developmental) I was expecting those 2 scores to be positively correlated.
What does the high negative correlation mean, biologically and how should I determine which score(s) is(are) accurate?
Andy
Dear developers,
Thank you for your useful tools.
I am currently working on a dataset where cell types are hard to define, thus we don't know if there are any progenitors.
I use the 5 scores (ESC+iPSC, EB, ED, ECTO, MESO) to see any correlations between those.
Something I cannot wrap my head around is why some scores are highly negatively correlated (e.g Embryoid bodies and ESC+iPSC, correlation=-0.9) in different samples. Because of their nature (developmental) I was expecting those 2 scores to be positively correlated.
What does the high negative correlation mean, biologically and how should I determine which score(s) is(are) accurate?
Andy