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<!DOCTYPE html>
<html class="no-js" lang="en">
<head>
<meta charset="utf-8" />
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<title>Startup Voucher | BreastScreening-AI</title>
<meta name="description" content="Startup Voucher operation, activities, evidence and reported results for BreastScreening-AI." />
<meta name="viewport" content="width=device-width, initial-scale=1" />
<meta property="og:title" content="Startup Voucher | BreastScreening-AI" />
<meta property="og:description" content="Objectives, activities and reported results from the BreastScreening-AI Startup Voucher operation." />
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<body class="evidence-page">
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<ul id="nav" class="navbar-nav ms-auto">
<li class="nav-item"><a href="#operation">Operation</a></li>
<li class="nav-item"><a href="#project-sheet">Ficha do Projeto</a></li>
<li class="nav-item"><a href="#clinical-results">Clinical results</a></li>
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<main>
<section class="report-hero" aria-labelledby="report-title">
<div class="container">
<p class="report-kicker">Startup Voucher 2025</p>
<h1 id="report-title">Operation, activities and results</h1>
<p class="report-lead">A public reporting view of BreastScreening-AI's human-centred clinical AI development, validation activities and supporting research.</p>
<div class="report-meta" aria-label="Report metadata">
<span><i class="lni lni-calendar"></i> Updated 14 June 2026</span>
<span><i class="lni lni-shield"></i> Preliminary clinical evidence</span>
<span><i class="lni lni-stats-up"></i> Project-level TRL 5, progressing toward TRL 6</span>
</div>
</div>
</section>
<nav class="report-subnav" aria-label="Report sections">
<div class="container">
<a href="#operation">Overview</a>
<a href="#project-sheet">Ficha do Projeto</a>
<a href="#readiness">Readiness</a>
<a href="#clinical-results">Current results</a>
<a href="#research">Previous results</a>
<a href="#support">Providers</a>
</div>
</nav>
<section id="operation" class="report-section operation-section">
<div class="container">
<div class="row align-items-start g-5">
<div class="col-lg-7">
<p class="section-label">Operation</p>
<h2>Clinical decision support designed around radiologists</h2>
<p>BreastScreening-AI develops and validates artificial intelligence tools that support the interpretation of breast imaging and clinical decision-making without replacing professional judgement. The operation combines multimodal imaging, human-computer interaction, clinical workflow integration and responsible AI evaluation.</p>
<h3>Objectives</h3>
<ul class="report-list">
<li>Improve the consistency and efficiency of breast imaging assessment.</li>
<li>Evaluate AI assistance in realistic clinical workflows with healthcare professionals.</li>
<li>Reduce avoidable diagnostic errors while preserving clinician control and accountability.</li>
<li>Prepare the technology, evidence and governance required for further clinical validation.</li>
</ul>
</div>
<div class="col-lg-5">
<aside class="funding-panel" aria-labelledby="funding-title">
<img src="assets/recognitions/startup_voucher_2025.png" alt="Startup Voucher 2025" />
<h2 id="funding-title">Funded operation</h2>
<p>This operation benefits from financial support from the Portuguese Recovery and Resilience Plan (PRR) and the European Union through the Startup Voucher programme.</p>
<a href="https://recuperarportugal.gov.pt/" target="_blank" rel="noopener noreferrer">Visit Recuperar Portugal <i class="lni lni-arrow-top-right"></i></a>
<a href="assets/recognitions/Sensiperception_Cartaz_VoucherStartups.pptx" download>Download the project poster <i class="lni lni-download"></i></a>
</aside>
</div>
</div>
</div>
</section>
<section id="project-sheet" class="report-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Ficha do Projeto</p>
<h2>Public project sheet and poster</h2>
<p>Project information for the Startup Voucher operation, including the public poster prepared for PRR and European Union communication visibility.</p>
</div>
<div class="method-panel">
<div style="position: relative; width: 100%; min-height: 620px; border: 1px solid rgba(16, 42, 67, 0.12); border-radius: 18px; overflow: hidden; background: #f8fbfd;">
<iframe
title="Ficha do Projeto - Sensiperception Startup Voucher poster"
src="https://view.officeapps.live.com/op/embed.aspx?src=https%3A%2F%2Fbreastscreeningai.github.io%2Fassets%2Frecognitions%2FSensiperception_Cartaz_VoucherStartups.pptx"
width="100%"
height="620"
frameborder="0"
loading="lazy"
allowfullscreen>
</iframe>
</div>
<p class="evidence-caveat"><i class="lni lni-information"></i> If the embedded viewer does not load, download the project poster directly.</p>
<a class="doi-link" href="assets/recognitions/Sensiperception_Cartaz_VoucherStartups.pptx" download>Download Ficha do Projeto <i class="lni lni-download"></i></a>
</div>
</div>
</section>
<section id="readiness" class="report-section readiness-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Technology readiness</p>
<h2>Progression from TRL 5 toward TRL 6</h2>
<p>The Hospital da Luz work provided evidence of integration and usability testing in a relevant clinical environment. This supports project-level TRL 5 progressing toward TRL 6, while not constituting formal TRL certification, regulatory authorization, or clinical deployment approval.</p>
</div>
<div class="trl-path" aria-label="Technology readiness progression from TRL 5 to TRL 6">
<article class="trl-step trl-current">
<span class="trl-number">TRL 5</span>
<div><h3>Validated prototype</h3><p>Core components and AI-assisted workflows evaluated in representative settings.</p></div>
</article>
<div class="trl-connector" aria-hidden="true"><i class="lni lni-arrow-right"></i></div>
<article class="trl-step trl-next">
<span class="trl-number">TRL 6</span>
<div><h3>Progressing toward demonstration</h3><p>Integration through Siemens syngo.via Frontier/OpenApps and usability activities with physicians contribute evidence toward this level.</p></div>
</article>
<div class="trl-connector trl-muted" aria-hidden="true"><i class="lni lni-arrow-right"></i></div>
<article class="trl-step trl-next">
<span class="trl-number">Next</span>
<div><h3>Broader validation</h3><p>Larger prospective studies, consolidated CHTMAD outcomes and formal regulatory evidence.</p></div>
</article>
</div>
<p class="evidence-caveat"><i class="lni lni-information"></i> The current project-level assessment is TRL 5 progressing toward TRL 6. This is not an external certification or clinical authorization.</p>
</div>
</section>
<section id="clinical-results" class="report-section evidence-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Clinical evidence</p>
<h2>Hospital da Luz exploratory pilot</h2>
<p>The pilot involved seven physicians and assessed workflow integration, usability and decision support. Results are preliminary, use a small sample and should not be interpreted as clinical efficacy claims.</p>
</div>
<div class="indicator-grid" aria-label="Hospital da Luz pilot indicators">
<article class="indicator indicator-pink">
<strong>+11.82</strong>
<span>percentage points</span>
<p>Exploratory improvement in triage-level decision accuracy.</p>
</article>
<article class="indicator indicator-green">
<strong>81.82%</strong>
<span>decision stability</span>
<p>Decisions that remained unchanged with AI assistance.</p>
</article>
<article class="indicator indicator-blue">
<strong>p = 0.0036</strong>
<span>exploratory analysis</span>
<p>Statistical result for the complementary triage analysis.</p>
</article>
<article class="indicator indicator-neutral">
<strong>7</strong>
<span>physicians</span>
<p>Participants in integration and usability activities.</p>
</article>
</div>
<div class="method-panel evidence-context">
<div>
<h3>Where the pilot showed measurable progress</h3>
<p>The clearest observed effect was a <strong>+11.82 percentage-point improvement</strong> in the complementary triage-level analysis, supported by the exploratory statistical result of <strong>p = 0.0036</strong>.</p>
<p>BI-RADS remained the primary clinical reference throughout the pilot. The triage analysis provides an additional view of decision support and is not intended to replace BI-RADS or clinical judgement.</p>
</div>
<dl>
<dt>Approximate subset</dt><dd>11 patients</dd>
<dt>Image volume</dt><dd>23 images</dd>
<dt>Paired observations</dt><dd>110</dd>
<dt>Environment</dt><dd>Siemens syngo.via Frontier/OpenApps</dd>
</dl>
</div>
<div class="table-responsive accessible-data">
<table class="table">
<caption>Accessible data table comparing previous research and current pilot evidence.</caption>
<thead><tr><th scope="col">Evidence period</th><th scope="col">Indicator</th><th scope="col">Reported value</th><th scope="col">Status</th></tr></thead>
<tbody>
<tr><td>Previous, 2022</td><td>False positives</td><td>27% decrease</td><td>Peer-reviewed research</td></tr>
<tr><td>Previous, 2022</td><td>False negatives</td><td>4% decrease</td><td>Peer-reviewed research</td></tr>
<tr><td>Previous, 2022</td><td>Positive expectations and satisfaction</td><td>91% of clinicians</td><td>Peer-reviewed research</td></tr>
<tr><td>Current, 2026</td><td>Triage-level decision accuracy change</td><td>+11.82 percentage points</td><td>Exploratory pilot</td></tr>
<tr><td>Current, 2026</td><td>Decision stability</td><td>81.82%</td><td>Descriptive pilot result</td></tr>
<tr><td>Current, 2026</td><td>Clinical classification framework</td><td>BI-RADS retained</td><td>Primary clinical reference</td></tr>
</tbody>
</table>
</div>
</div>
</section>
<section class="report-section chtmad-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Field validation</p>
<h2>CHTMAD / ULSTMAD research activities</h2>
<p>CHTMAD activities investigated clinical reporting, documentation and human-machine-readable report structures using anonymised cases under an ethics-approved research protocol.</p>
</div>
<div class="chart-layout timeline-layout">
<div id="chtmad-chart" class="plotly-chart" role="img" aria-label="Timeline showing three CHTMAD fieldwork periods between November 2025 and January 2026"></div>
<div class="method-panel">
<h3>Current reporting status</h3>
<p>Three fieldwork periods are documented: 17-21 November 2025, 5-9 January 2026 and 26-30 January 2026.</p>
<p>The available evidence supports reporting the activities and methodology. No consolidated quantitative outcome data was reported yet, so no CHTMAD timeline is published here.</p>
</div>
</div>
</div>
</section>
<section id="research" class="report-section research-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Scientific comparison</p>
<h2>Results reported in peer-reviewed research</h2>
<p>These figures provide research context only. They come from a different study design and sample and must not be combined statistically with the Hospital da Luz pilot.</p>
</div>
<div class="publication-summary">
<div class="method-panel publication-panel">
<p class="publication-year">Artificial Intelligence in Medicine, 2022</p>
<h3>BreastScreening-AI: Evaluating Medical Intelligent Agents for Human-AI Interactions</h3>
<p>A real-world case study compared clinician-only and clinician-AI scenarios with 45 clinicians from nine institutions.</p>
<ul class="report-list compact-list">
<li>27% decrease in false positives.</li>
<li>4% decrease in false negatives.</li>
<li>91% of clinicians reported positive expectations and perceptive satisfaction.</li>
<li>Time-to-diagnose decreased by three minutes per patient.</li>
</ul>
<a class="doi-link" href="https://doi.org/10.1016/j.artmed.2022.102285" target="_blank" rel="noopener noreferrer">Read the publication <i class="lni lni-arrow-top-right"></i></a>
</div>
</div>
<div class="table-responsive accessible-data">
<table class="table">
<caption>Published indicators from the 2022 peer-reviewed study.</caption>
<thead><tr><th scope="col">Published indicator</th><th scope="col">Reported result</th></tr></thead>
<tbody>
<tr><td>False positives</td><td>27% decrease</td></tr>
<tr><td>False negatives</td><td>4% decrease</td></tr>
<tr><td>Positive expectations and satisfaction</td><td>91% of clinicians</td></tr>
<tr><td>Time-to-diagnose</td><td>3 minutes less per patient</td></tr>
</tbody>
</table>
</div>
</div>
</section>
<section id="support" class="report-section support-section">
<div class="container">
<div class="section-heading">
<p class="section-label">Specialist support</p>
<h2>Contributors to operation readiness</h2>
<p>External organisations supported distinct technical, funding, legal, regulatory and intellectual-property workstreams.</p>
</div>
<div class="support-grid">
<article><h3><a href="https://snap.partners" target="_blank" rel="noopener noreferrer">SNAP <i class="lni lni-arrow-top-right"></i></a></h3><p>Proposal development, project management and business development support.</p></article>
<article><h3><a href="https://leyton.com" target="_blank" rel="noopener noreferrer">Leyton <i class="lni lni-arrow-top-right"></i></a></h3><p>Startup Voucher and PRR technical reporting, cost-eligibility and communication compliance support.</p></article>
<article><h3><a href="https://saveasip.com" target="_blank" rel="noopener noreferrer">SAVEAS <i class="lni lni-arrow-top-right"></i></a></h3><p>Intellectual-property consultancy, including Freedom-to-Operate and term-sheet work.</p></article>
<article><h3><a href="https://kgsa.pt" target="_blank" rel="noopener noreferrer">KGSA <i class="lni lni-arrow-top-right"></i></a></h3><p>Our legal provider, supporting the company with corporate, contractual and legal matters.</p></article>
<article><h3><a href="https://complear.com" target="_blank" rel="noopener noreferrer">Complear <i class="lni lni-arrow-top-right"></i></a></h3><p>Regulatory and independent-validation discussions for medical AI readiness.</p></article>
<article><h3><a href="https://aavanz.biz" target="_blank" rel="noopener noreferrer">AAVANZ <i class="lni lni-arrow-top-right"></i></a></h3><p>Supported the preparation of our EIC Pathfinder and Horizon Europe proposals.</p></article>
</div>
</div>
</section>
<section class="report-section disclosure-section">
<div class="container">
<div class="disclosure-inner">
<div>
<p class="section-label">Reporting note</p>
<h2>Transparent by design</h2>
</div>
<p>This page distinguishes confirmed pilot results, research activities and peer-reviewed evidence. Values are not pooled across studies. Clinical results remain preliminary until larger prospective validation and formal institutional review are completed.</p>
</div>
</div>
</section>
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