diff --git a/tracer/missing-nullability-files.csv b/tracer/missing-nullability-files.csv
index 64b040254928..a1b2f4a03ce9 100644
--- a/tracer/missing-nullability-files.csv
+++ b/tracer/missing-nullability-files.csv
@@ -585,7 +585,6 @@ src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/DirectSubmissi
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/DirectSubmission/ILoggingEventLegacyDuck.cs
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/DirectSubmission/LevelDuck.cs
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/DirectSubmission/LevelDuckExtensions.cs
-src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/AppenderAttachedImplIntegration.cs
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/ILoggingEvent.cs
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/NLog/DirectSubmission/NLogConstants.cs
 src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/NLog/LogsInjection/DiagnosticContextHelper.cs
diff --git a/tracer/src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/AppenderAttachedImplIntegration.cs b/tracer/src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/AppenderAttachedImplIntegration.cs
index fcb837269b32..b850322af03d 100644
--- a/tracer/src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/AppenderAttachedImplIntegration.cs
+++ b/tracer/src/Datadog.Trace/ClrProfiler/AutoInstrumentation/Logging/Log4Net/LogsInjection/AppenderAttachedImplIntegration.cs
@@ -3,10 +3,13 @@
 // This product includes software developed at Datadog (https://www.datadoghq.com/). Copyright 2017 Datadog, Inc.
 // </copyright>
 
+#nullable enable
+
 using System;
 using System.ComponentModel;
 using Datadog.Trace.ClrProfiler.AutoInstrumentation.Logging;
 using Datadog.Trace.ClrProfiler.CallTarget;
+using Datadog.Trace.Logging;
 
 namespace Datadog.Trace.ClrProfiler.AutoInstrumentation.Log4Net
 {
@@ -26,6 +29,9 @@ namespace Datadog.Trace.ClrProfiler.AutoInstrumentation.Log4Net
     [EditorBrowsable(EditorBrowsableState.Never)]
     public sealed class AppenderAttachedImplIntegration
     {
+        private static readonly IDatadogLogger Log = DatadogLogging.GetLoggerFor(typeof(AppenderAttachedImplIntegration));
+        private static bool _loggedNullSettings;
+
         /// <summary>
         /// OnMethodBegin callback
         /// </summary>
@@ -44,9 +50,25 @@ internal static CallTargetState OnMethodBegin<TTarget, TLoggingEvent>(TTarget in
 
             var tracer = Tracer.Instance;
 
-            var mutableSettings = tracer.CurrentTraceSettings.Settings;
+            var mutableSettings = tracer.CurrentTraceSettings?.Settings;
+            if (mutableSettings is null)
+            {
+                if (!_loggedNullSettings)
+                {
+                    _loggedNullSettings = true;
+                    Log.Debug("log4net logs-injection skipped: CurrentTraceSettings was null.");
+                }
+
+                return CallTargetState.GetDefault();
+            }
+
+            if (!mutableSettings.LogsInjectionEnabled)
+            {
+                return CallTargetState.GetDefault();
+            }
+
             var properties = loggingEvent.Properties;
-            if (mutableSettings.LogsInjectionEnabled && properties != null && !properties.Contains(CorrelationIdentifier.ServiceKey))
+            if (properties is not null && !properties.Contains(CorrelationIdentifier.ServiceKey))
             {
                 properties[CorrelationIdentifier.ServiceKey] = mutableSettings.DefaultServiceName;
                 properties[CorrelationIdentifier.VersionKey] = mutableSettings.ServiceVersion ?? string.Empty;
@@ -60,7 +82,7 @@ internal static CallTargetState OnMethodBegin<TTarget, TLoggingEvent>(TTarget in
                 }
             }
 
-            return new CallTargetState(scope: null, state: null);
+            return CallTargetState.GetDefault();
         }
 
         /// <summary>
@@ -73,7 +95,7 @@ internal static CallTargetState OnMethodBegin<TTarget, TLoggingEvent>(TTarget in
         /// <param name="exception">Exception instance in case the original code threw an exception.</param>
         /// <param name="state">Calltarget state value</param>
         /// <returns>A response value, in an async scenario will be T of Task of T</returns>
-        internal static CallTargetReturn<TReturn> OnMethodEnd<TTarget, TReturn>(TTarget instance, TReturn returnValue, Exception exception, in CallTargetState state)
+        internal static CallTargetReturn<TReturn> OnMethodEnd<TTarget, TReturn>(TTarget instance, TReturn returnValue, Exception? exception, in CallTargetState state)
         {
             return new CallTargetReturn<TReturn>(returnValue);
         }