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3 | 3 | #' A data frame containing metadata for samples from the Marthandan et al. |
4 | 4 | #' (2016) study (GEO code GSE63577). |
5 | 5 | #' |
6 | | -#' @docType data |
7 | 6 | #' @format A data frame with 45 rows and 6 columns: |
8 | 7 | #' \describe{ |
9 | 8 | #' \item{sampleID}{Unique sample identifier.} |
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26 | 25 | #' Senescence Associated Genes and Pathways in Primary Human Fibroblasts |
27 | 26 | #' Detected by RNA-Seq. PLoS One 2016;11(5):e0154531. PMID: 27140416 |
28 | 27 | #' |
29 | | -#' @usage data(metadata_example) |
30 | 28 | #' @keywords datasets |
31 | 29 | "metadata_example" |
32 | 30 |
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51 | 49 | #' For illustration and package size reduction, genes with variance in the |
52 | 50 | #' bottom 10% across samples were removed, retaining the 90% most variable genes |
53 | 51 | #' in the dataset. |
54 | | -#' @docType data |
| 52 | +#' |
55 | 53 | #' @format A numeric matrix with rows as genes (gene symbols) and columns as |
56 | 54 | #' samples (sample IDs). |
57 | 55 | #' |
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65 | 63 | #' Senescence Associated Genes and Pathways in Primary Human Fibroblasts |
66 | 64 | #' Detected by RNA-Seq. |
67 | 65 | #' *PLoS One* 2016;11(5):e0154531. PMID: 27140416 |
68 | | -#' @usage data(counts_example) |
| 66 | +#' |
69 | 67 | #' @keywords datasets |
70 | 68 | "counts_example" |
71 | 69 |
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72 | 70 | #' Example Gene Sets for Cellular Senescence |
73 | | -#' @docType data |
| 71 | +#' |
74 | 72 | #' @format A named list of length 3: |
75 | 73 | #' \describe{ |
76 | 74 | #' \item{Literature_Senescence}{Character vector of gene symbols. A small, |
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82 | 80 | #' A gene set from Hernandez-Segura et al. (2017), with directionality (+1 or -1).} |
83 | 81 | #' } |
84 | 82 | #' |
85 | | -#' @usage data(genesets_example) |
86 | | -#' @keywords datasets |
87 | 83 | #' @references Hernandez-Segura A, de Jong TV, Melov S, Guryev V, Campisi J, |
88 | 84 | #' Demaria M. Unmasking Transcriptional Heterogeneity in Senescent Cells. |
89 | 85 | #' *Curr Biol.* 2017 Sep 11;27(17):2652-2660.e4. doi: 10.1016/j.cub.2017.07.033. |
90 | 86 | #' Epub 2017 Aug 30. PMID: 28844647; PMCID: PMC5788810. |
| 87 | +#' @keywords datasets |
91 | 88 | "genesets_example" |
92 | 89 |
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