diff --git a/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.h b/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.h
index 1d1178f93da..818723157eb 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.h
+++ b/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.h
@@ -141,9 +141,11 @@ class ITK_TEMPLATE_EXPORT ConfidenceConnectedImageFilter : public ImageToImageFi
    * executed using the Update() method. */
   itkGetConstReferenceMacro(Variance, InputRealType);
 
-  /** Method to access seed container. */
-  virtual const SeedsContainerType &
-  GetSeeds() const;
+  /** Set/Get the seed container. */
+  /** @ITKStartGrouping */
+  itkSetMacro(Seeds, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds, SeedsContainerType);
+  /** @ITKEndGrouping */
 
   itkConceptMacro(InputHasNumericTraitsCheck, (Concept::HasNumericTraits<InputImagePixelType>));
   itkConceptMacro(OutputHasNumericTraitsCheck, (Concept::HasNumericTraits<OutputImagePixelType>));
diff --git a/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.hxx b/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.hxx
index 7f8018c98e8..e311c9b1f0e 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.hxx
+++ b/Modules/Segmentation/RegionGrowing/include/itkConfidenceConnectedImageFilter.hxx
@@ -69,14 +69,6 @@ ConfidenceConnectedImageFilter<TInputImage, TOutputImage>::AddSeed(const IndexTy
   this->Modified();
 }
 
-template <typename TInputImage, typename TOutputImage>
-auto
-ConfidenceConnectedImageFilter<TInputImage, TOutputImage>::GetSeeds() const -> const SeedsContainerType &
-{
-  itkDebugMacro("returning Seeds");
-  return this->m_Seeds;
-}
-
 template <typename TInputImage, typename TOutputImage>
 void
 ConfidenceConnectedImageFilter<TInputImage, TOutputImage>::PrintSelf(std::ostream & os, Indent indent) const
diff --git a/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.h b/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.h
index b7da78c114d..a12100e3a44 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.h
+++ b/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.h
@@ -89,6 +89,7 @@ class ITK_TEMPLATE_EXPORT ConnectedThresholdImageFilter : public ImageToImageFil
   using InputImagePixelType = typename InputImageType::PixelType;
   using IndexType = typename InputImageType::IndexType;
   using SeedContainerType = std::vector<IndexType>;
+  using SeedsContainerType = SeedContainerType;
   using SizeType = typename InputImageType::SizeType;
 
   using OutputImageType = TOutputImage;
@@ -110,9 +111,11 @@ class ITK_TEMPLATE_EXPORT ConnectedThresholdImageFilter : public ImageToImageFil
   void
   ClearSeeds();
 
-  /** Method to access seed container. */
-  virtual const SeedContainerType &
-  GetSeeds() const;
+  /** Set/Get the seed container. */
+  /** @ITKStartGrouping */
+  itkSetMacro(Seeds, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds, SeedsContainerType);
+  /** @ITKEndGrouping */
 
   /** Set/Get value to replace thresholded pixels. Pixels that lie *
    *  within Lower and Upper (inclusive) will be replaced with this
diff --git a/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.hxx b/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.hxx
index fc1d9825780..e7c17bb4d18 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.hxx
+++ b/Modules/Segmentation/RegionGrowing/include/itkConnectedThresholdImageFilter.hxx
@@ -69,13 +69,6 @@ ConnectedThresholdImageFilter<TInputImage, TOutputImage>::ClearSeeds()
   }
 }
 
-template <typename TInputImage, typename TOutputImage>
-auto
-ConnectedThresholdImageFilter<TInputImage, TOutputImage>::GetSeeds() const -> const SeedContainerType &
-{
-  return this->m_Seeds;
-}
-
 template <typename TInputImage, typename TOutputImage>
 void
 ConnectedThresholdImageFilter<TInputImage, TOutputImage>::GenerateInputRequestedRegion()
diff --git a/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.h b/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.h
index 6d563f0e7de..4310d297b9c 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.h
+++ b/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.h
@@ -144,10 +144,10 @@ class ITK_TEMPLATE_EXPORT IsolatedConnectedImageFilter : public ImageToImageFilt
 
   /** Method to access seed container */
   /** @ITKStartGrouping */
-  virtual const SeedsContainerType &
-  GetSeeds1() const;
-  virtual const SeedsContainerType &
-  GetSeeds2() const;
+  itkSetMacro(Seeds1, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds1, SeedsContainerType);
+  itkSetMacro(Seeds2, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds2, SeedsContainerType);
   /** @ITKEndGrouping */
   /** Set/Get the limit on the lower threshold value. The default is
    * the NonpositiveMin() for the InputPixelType. */
diff --git a/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.hxx b/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.hxx
index 9f8792ca6d4..d668794fd50 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.hxx
+++ b/Modules/Segmentation/RegionGrowing/include/itkIsolatedConnectedImageFilter.hxx
@@ -137,22 +137,6 @@ IsolatedConnectedImageFilter<TInputImage, TOutputImage>::ClearSeeds2()
   }
 }
 
-template <typename TInputImage, typename TOutputImage>
-auto
-IsolatedConnectedImageFilter<TInputImage, TOutputImage>::GetSeeds1() const -> const SeedsContainerType &
-{
-  itkDebugMacro("returning Seeds1");
-  return this->m_Seeds1;
-}
-
-template <typename TInputImage, typename TOutputImage>
-auto
-IsolatedConnectedImageFilter<TInputImage, TOutputImage>::GetSeeds2() const -> const SeedsContainerType &
-{
-  itkDebugMacro("returning Seeds2");
-  return this->m_Seeds2;
-}
-
 template <typename TInputImage, typename TOutputImage>
 void
 IsolatedConnectedImageFilter<TInputImage, TOutputImage>::GenerateData()
diff --git a/Modules/Segmentation/RegionGrowing/include/itkNeighborhoodConnectedImageFilter.h b/Modules/Segmentation/RegionGrowing/include/itkNeighborhoodConnectedImageFilter.h
index 4049de080cd..1516fb49bc0 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkNeighborhoodConnectedImageFilter.h
+++ b/Modules/Segmentation/RegionGrowing/include/itkNeighborhoodConnectedImageFilter.h
@@ -58,6 +58,8 @@ class ITK_TEMPLATE_EXPORT NeighborhoodConnectedImageFilter : public ImageToImage
   using IndexType = typename InputImageType::IndexType;
   using InputImageSizeType = typename InputImageType::SizeType;
 
+  using SeedsContainerType = std::vector<IndexType>;
+
   using OutputImageType = TOutputImage;
   using OutputImagePointer = typename OutputImageType::Pointer;
   using OutputImageRegionType = typename OutputImageType::RegionType;
@@ -78,6 +80,12 @@ class ITK_TEMPLATE_EXPORT NeighborhoodConnectedImageFilter : public ImageToImage
   void
   AddSeed(const IndexType & seed);
 
+  /** Set/Get the seed container. */
+  /** @ITKStartGrouping */
+  itkSetMacro(Seeds, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds, SeedsContainerType);
+  /** @ITKEndGrouping */
+
   /** Set/Get the lower threshold. The default is 0. */
   /** @ITKStartGrouping */
   itkSetMacro(Lower, InputImagePixelType);
@@ -115,7 +123,7 @@ class ITK_TEMPLATE_EXPORT NeighborhoodConnectedImageFilter : public ImageToImage
 protected:
   NeighborhoodConnectedImageFilter();
   ~NeighborhoodConnectedImageFilter() override = default;
-  std::vector<IndexType> m_Seeds{};
+  SeedsContainerType m_Seeds{};
 
   InputImagePixelType m_Lower{};
   InputImagePixelType m_Upper{};
diff --git a/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.h b/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.h
index ce9a5e0d485..28b3e206b97 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.h
+++ b/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.h
@@ -140,9 +140,11 @@ class ITK_TEMPLATE_EXPORT VectorConfidenceConnectedImageFilter : public ImageToI
   const CovarianceMatrixType &
   GetCovariance() const;
 
-  /** Method to access seed container */
-  virtual const SeedsContainerType &
-  GetSeeds() const;
+  /** Set/Get the seed container. */
+  /** @ITKStartGrouping */
+  itkSetMacro(Seeds, SeedsContainerType);
+  itkGetConstReferenceMacro(Seeds, SeedsContainerType);
+  /** @ITKEndGrouping */
 
   itkConceptMacro(OutputEqualityComparableCheck, (Concept::EqualityComparable<OutputImagePixelType>));
   itkConceptMacro(InputHasNumericTraitsCheck, (Concept::HasNumericTraits<typename InputImagePixelType::ValueType>));
diff --git a/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.hxx b/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.hxx
index 24d08b51b1f..1e4bc5d7758 100644
--- a/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.hxx
+++ b/Modules/Segmentation/RegionGrowing/include/itkVectorConfidenceConnectedImageFilter.hxx
@@ -352,14 +352,6 @@ VectorConfidenceConnectedImageFilter<TInputImage, TOutputImage>::GetMean() const
   return m_ThresholdFunction->GetMean();
 }
 
-template <typename TInputImage, typename TOutputImage>
-auto
-VectorConfidenceConnectedImageFilter<TInputImage, TOutputImage>::GetSeeds() const -> const SeedsContainerType &
-{
-  itkDebugMacro("returning Seeds");
-  return this->m_Seeds;
-}
-
 } // end namespace itk
 
 #endif
diff --git a/Modules/Segmentation/RegionGrowing/test/itkConfidenceConnectedImageFilterTest.cxx b/Modules/Segmentation/RegionGrowing/test/itkConfidenceConnectedImageFilterTest.cxx
index 1a26b004a13..3f49aa75462 100644
--- a/Modules/Segmentation/RegionGrowing/test/itkConfidenceConnectedImageFilterTest.cxx
+++ b/Modules/Segmentation/RegionGrowing/test/itkConfidenceConnectedImageFilterTest.cxx
@@ -102,6 +102,22 @@ itkConfidenceConnectedImageFilterTest(int argc, char * argv[])
   // Exercise AddSeed() method
   filter->AddSeed(seed);
 
+  // Exercise SetSeeds/GetSeeds container interface
+  const FilterType::SeedsContainerType seeds = filter->GetSeeds();
+  filter->ClearSeeds();
+  if (!filter->GetSeeds().empty())
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container not empty after ClearSeeds." << std::endl;
+    return EXIT_FAILURE;
+  }
+  filter->SetSeeds(seeds);
+  if (filter->GetSeeds() != seeds)
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container from GetSeeds does not match SetSeeds input." << std::endl;
+    return EXIT_FAILURE;
+  }
 
   return EXIT_SUCCESS;
 }
diff --git a/Modules/Segmentation/RegionGrowing/test/itkConnectedThresholdImageFilterTest.cxx b/Modules/Segmentation/RegionGrowing/test/itkConnectedThresholdImageFilterTest.cxx
index cfdcd87c1cc..28ba82b16dc 100644
--- a/Modules/Segmentation/RegionGrowing/test/itkConnectedThresholdImageFilterTest.cxx
+++ b/Modules/Segmentation/RegionGrowing/test/itkConnectedThresholdImageFilterTest.cxx
@@ -79,6 +79,18 @@ itkConnectedThresholdImageFilterTest(int argc, char * argv[])
     return EXIT_FAILURE;
   }
 
+  // Exercise SetSeeds/GetSeeds container interface using SeedsContainerType alias
+  connectedThresholdFilter->AddSeed(seed);
+  const ConnectedThresholdImageFilterType::SeedsContainerType seeds = connectedThresholdFilter->GetSeeds();
+  connectedThresholdFilter->ClearSeeds();
+  connectedThresholdFilter->SetSeeds(seeds);
+  if (connectedThresholdFilter->GetSeeds() != seeds)
+  {
+    std::cerr << "Test FAILED !" << std::endl;
+    std::cerr << "Seed container from GetSeeds does not match SetSeeds input." << std::endl;
+    return EXIT_FAILURE;
+  }
+
   connectedThresholdFilter->SetSeed(seed);
 
 
diff --git a/Modules/Segmentation/RegionGrowing/test/itkIsolatedConnectedImageFilterTest.cxx b/Modules/Segmentation/RegionGrowing/test/itkIsolatedConnectedImageFilterTest.cxx
index 0643668801b..cb0f3c1c474 100644
--- a/Modules/Segmentation/RegionGrowing/test/itkIsolatedConnectedImageFilterTest.cxx
+++ b/Modules/Segmentation/RegionGrowing/test/itkIsolatedConnectedImageFilterTest.cxx
@@ -75,6 +75,29 @@ itkIsolatedConnectedImageFilterTest(int argc, char * argv[])
     filter->AddSeed2(seed1);
   }
 
+  // Exercise the seed-container accessors. Round-trip the populated
+  // containers through SetSeeds/GetSeeds, leaving the filter unchanged.
+  const FilterType::SeedsContainerType seeds1 = filter->GetSeeds1();
+  const FilterType::SeedsContainerType seeds2 = filter->GetSeeds2();
+
+  filter->ClearSeeds1();
+  filter->ClearSeeds2();
+  if (!filter->GetSeeds1().empty() || !filter->GetSeeds2().empty())
+  {
+    std::cerr << "Test failed!" << std::endl;
+    std::cerr << "Seed containers were not cleared by ClearSeeds." << std::endl;
+    return EXIT_FAILURE;
+  }
+
+  filter->SetSeeds1(seeds1);
+  filter->SetSeeds2(seeds2);
+  if (filter->GetSeeds1() != seeds1 || filter->GetSeeds2() != seeds2)
+  {
+    std::cerr << "Test failed!" << std::endl;
+    std::cerr << "Seed containers retrieved by GetSeeds do not match those set by SetSeeds." << std::endl;
+    return EXIT_FAILURE;
+  }
+
   // The min and max values for a .png image
   constexpr FilterType::InputImagePixelType lower{ 0 };
   filter->SetLower(lower);
diff --git a/Modules/Segmentation/RegionGrowing/test/itkNeighborhoodConnectedImageFilterTest.cxx b/Modules/Segmentation/RegionGrowing/test/itkNeighborhoodConnectedImageFilterTest.cxx
index 273400fccc5..d037877e899 100644
--- a/Modules/Segmentation/RegionGrowing/test/itkNeighborhoodConnectedImageFilterTest.cxx
+++ b/Modules/Segmentation/RegionGrowing/test/itkNeighborhoodConnectedImageFilterTest.cxx
@@ -83,5 +83,22 @@ itkNeighborhoodConnectedImageFilterTest(int argc, char * argv[])
   writer->SetFileName(argv[2]);
   writer->Update();
 
+  // Exercise SetSeeds/GetSeeds container interface
+  const FilterType::SeedsContainerType seeds = filter->GetSeeds();
+  filter->ClearSeeds();
+  if (!filter->GetSeeds().empty())
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container not empty after ClearSeeds." << std::endl;
+    return EXIT_FAILURE;
+  }
+  filter->SetSeeds(seeds);
+  if (filter->GetSeeds() != seeds)
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container from GetSeeds does not match SetSeeds input." << std::endl;
+    return EXIT_FAILURE;
+  }
+
   return EXIT_SUCCESS;
 }
diff --git a/Modules/Segmentation/RegionGrowing/test/itkVectorConfidenceConnectedImageFilterTest.cxx b/Modules/Segmentation/RegionGrowing/test/itkVectorConfidenceConnectedImageFilterTest.cxx
index 9ad24b5af45..06868a4fbae 100644
--- a/Modules/Segmentation/RegionGrowing/test/itkVectorConfidenceConnectedImageFilterTest.cxx
+++ b/Modules/Segmentation/RegionGrowing/test/itkVectorConfidenceConnectedImageFilterTest.cxx
@@ -104,6 +104,23 @@ itkVectorConfidenceConnectedImageFilterTest(int argc, char * argv[])
   writer->SetFileName(argv[2]);
   writer->Update();
 
+  // Exercise SetSeeds/GetSeeds container interface
+  const FilterType::SeedsContainerType seeds = filter->GetSeeds();
+  filter->ClearSeeds();
+  if (!filter->GetSeeds().empty())
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container not empty after ClearSeeds." << std::endl;
+    return EXIT_FAILURE;
+  }
+  filter->SetSeeds(seeds);
+  if (filter->GetSeeds() != seeds)
+  {
+    std::cerr << "Test FAILED!" << std::endl;
+    std::cerr << "Seed container from GetSeeds does not match SetSeeds input." << std::endl;
+    return EXIT_FAILURE;
+  }
+
   // Exercise SetSeed() method
   filter->SetSeed(seed1);