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<!doctype html><html lang=en-us><head><meta charset=utf-8><meta name=viewport content="width=device-width,initial-scale=1"><meta http-equiv=X-UA-Compatible content="IE=edge"><meta name=generator content="Hugo Blox Builder 5.9.7"><link rel=preconnect href=https://fonts.gstatic.com crossorigin><link rel=preload as=style href="https://fonts.googleapis.com/css2?family=Montserrat:wght@400;700&family=Roboto+Mono&family=Roboto:wght@400;700&display=swap"><link rel=stylesheet href="https://fonts.googleapis.com/css2?family=Montserrat:wght@400;700&family=Roboto+Mono&family=Roboto:wght@400;700&display=swap" media=print onload='this.media="all"'><link rel=stylesheet href=/css/vendor-bundle.min.26c458e6907dc03073573976b7f4044e.css media=print onload='this.media="all"'><link rel=stylesheet href=https://cdn.jsdelivr.net/gh/jpswalsh/academicons@1.9.4/css/academicons.min.css integrity="sha512-IW0nhlW5MgNydsXJO40En2EoCkTTjZhI3yuODrZIc8cQ4h1XcF53PsqDHa09NqnkXuIe0Oiyyj171BqZFwISBw==" crossorigin=anonymous media=print onload='this.media="all"'><link rel=stylesheet href=https://cdn.jsdelivr.net/npm/leaflet@1.7.1/dist/leaflet.min.css integrity crossorigin=anonymous media=print onload='this.media="all"'><link rel=stylesheet href=/css/wowchemy.be54b2fcffe7fa2270bd8120a3f1ecb6.css><link rel=stylesheet href=/css/libs/chroma/github-light.min.css title=hl-light media=print onload='this.media="all"'><link rel=stylesheet href=/css/libs/chroma/dracula.min.css title=hl-dark media=print onload='this.media="all"' disabled><meta name=author content="Florian Buettner"><meta name=description content="Machine Learning in Oncology — research group of Prof. Florian Buettner."><link rel=alternate hreflang=en-us href=https://mlo-lab.github.io/><link rel=canonical href=https://mlo-lab.github.io/><link rel=manifest href=/manifest.webmanifest><link rel=icon type=image/png href=/media/icon_hu_fce52e938d1d5d54.png><link rel=apple-touch-icon type=image/png href=/media/icon_hu_95a8b0da9d296a5f.png><meta name=theme-color content="#1565c0"><meta property="twitter:card" content="summary"><meta property="twitter:image" content="https://mlo-lab.github.io/media/logo_hu_9ab0b13d2686246a.png"><meta property="og:type" content="website"><meta property="og:site_name" content="MLO Lab"><meta property="og:url" content="https://mlo-lab.github.io/"><meta property="og:title" content="MLO Lab"><meta property="og:description" content="Machine Learning in Oncology — research group of Prof. Florian Buettner."><meta property="og:image" content="https://mlo-lab.github.io/media/logo_hu_9ab0b13d2686246a.png"><meta property="og:locale" content="en-us"><meta property="og:updated_time" content="2024-01-01T00:00:00+00:00"><script type=application/ld+json>{"@context":"https://schema.org","@type":"WebSite","potentialAction":{"@type":"SearchAction","target":"https://mlo-lab.github.io/?q={search_term_string}","query-input":"required name=search_term_string"},"url":"https://mlo-lab.github.io/"}</script><script type=application/ld+json>{"@context":"https://schema.org","@type":"Organization","@id":"https://mlo-lab.github.io/","name":"MLO Lab","logo":"https://mlo-lab.github.io/media/logo_hu_b0d95015d452a11.png","url":"https://mlo-lab.github.io/"}</script><link rel=alternate href=/index.xml type=application/rss+xml title="MLO Lab"><title>MLO Lab</title></head><body id=top data-spy=scroll data-offset=70 data-target=#navbar-main class=page-wrapper data-wc-page-id=3976528693a0108357f4928017600865><script src=/js/wowchemy-init.min.9e4214442a7711d35691acd58f6f6361.js></script><aside class=search-modal id=search><div class=container><section class=search-header><div class="row no-gutters justify-content-between mb-3"><div class=col-6><h1>Search</h1></div><div class="col-6 col-search-close"><a class=js-search href=# aria-label=Close><i class="fas fa-times-circle text-muted" aria-hidden=true></i></a></div></div><div id=search-box><input name=q id=search-query placeholder=Search... autocapitalize=off autocomplete=off autocorrect=off spellcheck=false type=search class=form-control aria-label=Search...></div></section><section class=section-search-results><div id=search-hits></div></section></div></aside><div class="page-header header--fixed"><header><nav class="navbar navbar-expand-lg navbar-light compensate-for-scrollbar" id=navbar-main><div class=container-xl><div class="d-none d-lg-inline-flex"><a class=navbar-brand href=/><img src=/media/logo_hu_5fac6fcf19d5ad1b.png alt="MLO Lab"></a></div><button type=button class=navbar-toggler data-toggle=collapse data-target=#navbar-content aria-controls=navbar-content aria-expanded=false aria-label="Toggle navigation">
<span><i class="fas fa-bars"></i></span></button><div class="navbar-brand-mobile-wrapper d-inline-flex d-lg-none"><a class=navbar-brand href=/><img src=/media/logo_hu_5fac6fcf19d5ad1b.png alt="MLO Lab"></a></div><div class="navbar-collapse main-menu-item collapse justify-content-end" id=navbar-content><ul class="navbar-nav d-md-inline-flex"><li class=nav-item><a class=nav-link href=/#about data-target=#about><span>About</span></a></li><li class=nav-item><a class=nav-link href=/#news data-target=#news><span>News</span></a></li><li class=nav-item><a class=nav-link href=/#projects data-target=#projects><span>Projects</span></a></li><li class=nav-item><a class=nav-link href=/#publications data-target=#publications><span>Publications</span></a></li><li class=nav-item><a class=nav-link href=/#people data-target=#people><span>Team</span></a></li><li class=nav-item><a class=nav-link href=/#teaching data-target=#teaching><span>Teaching</span></a></li><li class=nav-item><a class=nav-link href=/#jobs data-target=#jobs><span>Jobs</span></a></li><li class=nav-item><a class=nav-link href=/#contact data-target=#contact><span>Contact</span></a></li></ul></div><ul class="nav-icons navbar-nav flex-row ml-auto d-flex pl-md-2"><li class=nav-item><a class="nav-link js-search" href=# aria-label=Search><i class="fas fa-search" aria-hidden=true></i></a></li><li class="nav-item dropdown theme-dropdown"><a href=# class=nav-link data-toggle=dropdown aria-haspopup=true aria-label="Display preferences"><i class="fas fa-moon" aria-hidden=true></i></a><div class=dropdown-menu><a href=# class="dropdown-item js-set-theme-light"><span>Light</span>
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</a><a href=# class="dropdown-item js-set-theme-auto"><span>Automatic</span></a></div></li></ul></div></nav></header></div><div class=page-body><span class="js-widget-page d-none"></span><section id=home class="home-section wg-hero dark fullscreen"><div class="home-section-bg bg-image parallax" style=background-image:url(https://mlo-lab.github.io/media/background_mlo_hu_759948d22660966d.webp);background-size:cover;background-position:50%></div><div class=container><h1 class=hero-title>MLO Lab</h1><div class=hero-lead><strong>Machine Learning in Oncology</strong></div></div></section><section id=about class="home-section wg-about-biography"><div class=home-section-bg></div><div class=container><div class=row><div class="col-12 col-lg-4"><div id=profile><div class=portrait-title><h2>MLO Lab</h2><h3><a href=https://www.uni-frankfurt.de target=_blank rel=noopener><span>Goethe University Frankfurt</span></a></h3><h3><a href=https://dktk.dkfz.de target=_blank rel=noopener><span>German Cancer Consortium (DKTK)</span></a></h3><h3><a href=https://www.dkfz.de target=_blank rel=noopener><span>German Cancer Research Center (DKFZ)</span></a></h3></div><ul class=network-icon aria-hidden=true><li><a href=/#contact aria-label=envelope><i class="fas fa-envelope big-icon"></i></a></li><li><a href="https://scholar.google.com/citations?user=AaPKbPAAAAAJ" target=_blank rel=noopener aria-label=graduation-cap><i class="fas fa-graduation-cap big-icon"></i></a></li><li><a href=https://www.linkedin.com/company/machine-learning-in-oncology-lab/ target=_blank rel=noopener aria-label=linkedin><i class="fab fa-linkedin big-icon"></i></a></li><li><a href=https://x.com/mlo_lab/ target=_blank rel=noopener aria-label=x-twitter><i class="fab fa-x-twitter big-icon"></i></a></li><li><a href=https://github.com/mlo-lab target=_blank rel=noopener aria-label=github><i class="fab fa-github big-icon"></i></a></li></ul></div></div><div class="col-12 col-lg-8"><h1>Who we are</h1><div class=article-style><p>Our mission is the application and collaboration driven development of interpretable and statistically sound machine learning methods for understanding disease heterogeneity.
As part of the DKTK/DKFZ and hosted by Frankfurt University we thrive to use machine learning for accelerating progress in personalised oncology.</p><p>We build on probabilistic machine learning to address computational challenges in three areas: translational single-cell genomics, computational proteomics and the integration of multi-omics data.</p></div><div class=row></div></div></div><div class="row group-photo"><div class=col-12><img src=/media/group_cropped_hu_6dd07f3b9214c664.webp width=1399 height=1400 alt="MLO Lab group photo" loading=lazy></div></div></div></section><section id=news class="home-section wg-markdown"><div class=home-section-bg></div><div class=container><div class="row justify-content-center"><div class="section-heading col-12 mb-3 text-center"><h1 class=mb-0>News</h1></div><div class=col-12><div class=sk-ww-linkedin-page-post data-embed-id=25689224></div><script src=https://widgets.sociablekit.com/linkedin-page-posts/widget.js defer></script></div></div></div></section><section id=projects class="home-section wg-portfolio"><div class=home-section-bg></div><div class=container><div class="row justify-content-center"><div class="section-heading col-12 mb-3 text-center"><h1 class=mb-0>Projects</h1></div><div class=col-12><span class="d-none default-project-filter">*</span><div class=project-toolbar><div class=project-filters><div class="btn-toolbar d-flex justify-content-center"><div class="btn-group flex-wrap"><a href=# data-filter=* class="btn btn-primary btn-lg active">All</a>
<a href=# data-filter=.js-id-trustworthy-ml class="btn btn-primary btn-lg">Trustworthy Machine Learning</a>
<a href=# data-filter=.js-id-applied-bioinformatics class="btn btn-primary btn-lg">Applied Bioinformatics</a>
<a href=# data-filter=.js-id-multi-omics class="btn btn-primary btn-lg">Multi-Omics Tools</a></div></div></div></div><div class="isotope projects-container row js-layout-row"><div class="col-12 isotope-item js-id-applied-bioinformatics js-id-single-cell js-id-medical-imaging"><div class="card-simple view-card"><div class=article-metadata><div><span><a href=/author/sarmad-ahmad-khan/>Sarmad Ahmad Khan</a></span>, <span><a href=/author/yihao-liu/>Yihao Liu</a></span></div><span class=article-date>Sep 24, 2025</span></div><a href=/project/medical-imaging/><div class=img-hover-zoom><img src=/project/medical-imaging/featured_hu_4bf95172894a9273.webp height=240 width=800 class=article-banner alt="Quantitative Imaging in Oncology" loading=lazy></div></a><div class="section-subheading article-title mb-1 mt-3"><a href=/project/medical-imaging/>Quantitative Imaging in Oncology</a></div><a href=/project/medical-imaging/ class=summary-link><div class=article-style><p>Quantitative imaging in oncology uses advanced microscopy, image analysis, and machine learning to study cancer in unprecedented detail. By extracting rich spatial and molecular information from tissues, we aim to better understand how tumors grow, respond to treatments, and interact with their surroundings.</p></div></a></div></div><div class="col-12 isotope-item js-id-trustworthy-ml"><div class="card-simple view-card"><div class=article-metadata><div><span><a href=/author/achim-hekler/>Achim Hekler</a></span>, <span><a href=/author/giuseppe-serra/>Giuseppe Serra</a></span>, <span><a href=/author/lukas-kuhn/>Lukas Kuhn</a></span>, <span><a href=/author/nassim-walha/>Nassim Walha</a></span>, <span><a href=/author/sebastian-gruber/>Sebastian Gruber</a></span></div><span class=article-date>Jun 10, 2025</span></div><a href=/project/trustworthy-ml/><div class=img-hover-zoom><img src=/project/trustworthy-ml/featured_hu_2ca7de15dbebaebf.webp height=403 width=800 class=article-banner alt="Trustworthy Machine Learning in Biomedical Research" loading=lazy></div></a><div class="section-subheading article-title mb-1 mt-3"><a href=/project/trustworthy-ml/>Trustworthy Machine Learning in Biomedical Research</a></div><a href=/project/trustworthy-ml/ class=summary-link><div class=article-style><p>As machine learning becomes increasingly central to biomedical discovery and clinical decision-making, ensuring the reliability, fairness, and interpretability of these models is critical. In our lab, we are committed to developing and applying machine learning methods that are not only accurate but also trustworthy.</p></div></a></div></div><div class="col-12 isotope-item js-id-applied-bioinformatics js-id-single-cell"><div class="card-simple view-card"><div class=article-metadata><div><span><a href=/author/adrien-jolly/>Adrien Jolly</a></span>, <span><a href=/author/ali-yavuz-cak%C4%B1r/>Ali Yavuz Çakır</a></span>, <span><a href=/author/sarmad-ahmad-khan/>Sarmad Ahmad Khan</a></span>, <span><a href=/author/yihao-liu/>Yihao Liu</a></span>, <span><a href=/author/tyra-stickel/>Tyra Stickel</a></span></div><span class=article-date>Jun 10, 2025</span></div><div class="section-subheading article-title mb-1 mt-3"><a href=/project/comp-medicine/>Computational Molecular Medicine</a></div><a href=/project/comp-medicine/ class=summary-link><div class=article-style><p>Single-cell multi-omics data present unique challenges. Our lab combines advanced computational methods with high-dimensional biological data to uncover mechanisms of disease, with a particular emphasis on cancer and metabolic disorders.</p></div></a></div></div><div class="col-12 isotope-item js-id-latent-variable-models js-id-multi-omics js-id-domain-expertise js-id-gaussian-process js-id-tensor-decomposition js-id-pathway-analysis"><div class="card-simple view-card"><div class=article-metadata><div><span><a href=/author/arber-qoku/>Arber Qoku</a></span>, <span><a href=/author/kevin-de-azevedo/>Kevin De Azevedo</a></span>, <span><a href=/author/zahra-moslehi/>Zahra Moslehi</a></span>, <span><a href=/author/sareh-ameri-far/>Sareh Ameri Far</a></span>, <span><a href=/author/tyra-stickel/>Tyra Stickel</a></span>, <span><a href=/author/yusuf-berk-oruc/>Yusuf Berk Oruc</a></span></div><span class=article-date>Jun 10, 2025</span></div><a href=/project/multi-omics/><div class=img-hover-zoom><img src=/project/multi-omics/featured_hu_5d1d2cae162ca808.webp height=454 width=800 class=article-banner alt="Interpretable Integration of Multi-Omics Data" loading=lazy></div></a><div class="section-subheading article-title mb-1 mt-3"><a href=/project/multi-omics/>Interpretable Integration of Multi-Omics Data</a></div><a href=/project/multi-omics/ class=summary-link><div class=article-style><p>Understanding the complexity of cancer requires making sense of equally complex biological data. In our lab, we develop probabilistic models for the integration of multi-omics datasets to uncover hidden structure in the data by capturing both shared and modality-specific sources of variation.</p></div></a><div class=btn-links><a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/MLO-lab/MuVI/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>MuVI</a>
<a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/MLO-lab/MOMO-GP/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>MOMO-GP</a>
<a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/bioFAM/joanapy/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>JOANA</a>
<a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/bioFAM/mofaflex/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>MOFA-FLEX</a>
<a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/MLO-lab/pacmon/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>PACMON</a>
<a class="btn btn-outline-primary btn-page-header btn-sm" href=https://github.com/MLO-lab/MANTRA/ target=_blank rel=noopener><i class="fab fa-github mr-1"></i>MANTRA</a></div></div></div></div></div></div></div></section><section id=publications class="home-section wg-collection"><div class=home-section-bg></div><div class=container><div class="row justify-content-center"><div class="section-heading col-12 mb-3 text-center"><h1 class=mb-0>Publication Highlights</h1></div><div class=col-12><div class="pub-list-item view-citation" style=margin-bottom:1rem><i class="far fa-file-alt pub-icon" aria-hidden=true></i>
<span class="article-metadata li-cite-author"><span><a href=/author/nassim-walha/>Nassim Walha</a></span>, <span><a href=/author/sebastian-g-gruber/>Sebastian G Gruber</a></span>, <span><a href=/author/thomas-decker/>Thomas Decker</a></span>, <span><a href=/author/yinchong-yang/>Yinchong Yang</a></span>, <span><a href=/author/alireza-javanmardi/>Alireza Javanmardi</a></span>, <span><a href=/author/eyke-hullermeier/>Eyke Hüllermeier</a></span>, <span><a href=/author/florian-buettner/>Florian Buettner</a></span>
</span>(2026).
<a href=/publication/walha-2026-fine/>Fine-grained uncertainty decomposition in large language models: A spectral approach</a>.
<em>Proceedings of the AAAI Conference on Artificial Intelligence</em>.<p><a href=# class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename=/publication/walha-2026-fine/cite.bib>Cite</a></p></div><div class="pub-list-item view-citation" style=margin-bottom:1rem><i class="far fa-file-alt pub-icon" aria-hidden=true></i>
<span class="article-metadata li-cite-author"><span><a href=/author/julius-c-enssle/>Julius C Enssle</a></span>, <span><a href=/author/bjorn-haupl/>Björn Häupl</a></span>, <span><a href=/author/arber-qoku/>Arber Qoku</a></span>, <span><a href=/author/boya-wang/>Boya Wang</a></span>, <span><a href=/author/george-w-wright/>George W Wright</a></span>, <span><a href=/author/sharon-barrans/>Sharon Barrans</a></span>, <span><a href=/author/yulai-zhou/>Yulai Zhou</a></span>, <span><a href=/author/matthew-a-care/>Matthew a Care</a></span>, <span><a href=/author/cathy-burton/>Cathy Burton</a></span>, <span><a href=/author/caitlin-gribbin/>Caitlin Gribbin</a></span>, <span><a href=/author/others/>Others</a></span>
</span>(2026).
<a href=/publication/enssle-2026-pathogenesis/>Pathogenesis of diffuse large B cell lymphoma proteogenotypes</a>.
<em>Cancer Cell</em>.<p><a href=# class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename=/publication/enssle-2026-pathogenesis/cite.bib>Cite</a></p></div><div class="pub-list-item view-citation" style=margin-bottom:1rem><i class="far fa-file-alt pub-icon" aria-hidden=true></i>
<span class="article-metadata li-cite-author"><span><a href=/author/sebastian-gregor-gruber/>Sebastian Gregor Gruber</a></span>, <span><a href=/author/florian-buettner/>Florian Buettner</a></span>
</span>(2024).
<a href=/publication/gruber-2024-bias/>A Bias-Variance-Covariance Decomposition of Kernel Scores for Generative Models</a>.
<em>International Conference on Machine Learning</em>.<p><a href=# class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename=/publication/gruber-2024-bias/cite.bib>Cite</a></p></div><div class="pub-list-item view-citation" style=margin-bottom:1rem><i class="far fa-file-alt pub-icon" aria-hidden=true></i>
<span class="article-metadata li-cite-author"><span><a href=/author/lena-maier-hein/>Lena Maier-Hein</a></span>, <span><a href=/author/annika-reinke/>Annika Reinke</a></span>, <span><a href=/author/patrick-godau/>Patrick Godau</a></span>, <span><a href=/author/minu-d-tizabi/>Minu D Tizabi</a></span>, <span><a href=/author/florian-buettner/>Florian Buettner</a></span>, <span><a href=/author/evangelia-christodoulou/>Evangelia Christodoulou</a></span>, <span><a href=/author/ben-glocker/>Ben Glocker</a></span>, <span><a href=/author/fabian-isensee/>Fabian Isensee</a></span>, <span><a href=/author/jens-kleesiek/>Jens Kleesiek</a></span>, <span><a href=/author/michal-kozubek/>Michal Kozubek</a></span>, <span><a href=/author/others/>Others</a></span>
</span>(2024).
<a href=/publication/maier-2024-metrics/>Metrics reloaded: recommendations for image analysis validation</a>.
<em>Nature methods</em>.<p><a href=# class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename=/publication/maier-2024-metrics/cite.bib>Cite</a></p></div><div class="pub-list-item view-citation" style=margin-bottom:1rem><i class="far fa-file-alt pub-icon" aria-hidden=true></i>
<span class="article-metadata li-cite-author"><span><a href=/author/arber-qoku/>Arber Qoku</a></span>, <span><a href=/author/florian-buettner/>Florian Buettner</a></span>
</span>(2023).
<a href=/publication/qoku-2023-encoding/>Encoding domain knowledge in multi-view latent variable models: A bayesian approach with structured sparsity</a>.
<em>International Conference on Artificial Intelligence and Statistics</em>.<p><a href=# class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename=/publication/qoku-2023-encoding/cite.bib>Cite</a></p></div><div class=see-all><a href=/publication>Explore all publications
<i class="fas fa-angle-right"></i></a></div></div></div></div></section><section id=people class="home-section wg-people"><div class=home-section-bg></div><div class=container><div class="row justify-content-center people-widget"><div class="section-heading col-12 mb-3 text-center"><h1 class=mb-0>Team</h1></div><div class="col-md-12 people-group--principal-investigators"><h2 class=mb-4>Principal Investigators</h2></div><div class="col-12 col-sm-auto people-person people-group--principal-investigators"><a href=/author/florian-buettner/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/florian-buettner/avatar_hu_c17f396a46c5b9ea.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/florian-buettner/>Florian Buettner</a></h2><h3>Professor for Bioinformatics in Oncology</h3><p class=people-interests>Machine Learning (ML), Precision Oncology, Multi-omics data integration</p></div></div><div class="col-md-12 people-group--scientific-coordinators"><h2 class=mb-4>Scientific Coordinators</h2></div><div class="col-12 col-sm-auto people-person people-group--scientific-coordinators"><a href=/author/bernhard-hellmann/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/bernhard-hellmann/avatar_hu_cb15c45b088815c4.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/bernhard-hellmann/>Bernhard Hellmann</a></h2><h3>Scientific Coordinator</h3><p class=people-interests>Nutritional Sciences, Clinical Data Management, Interdisciplinary Biomedical Research</p></div></div><div class="col-md-12 people-group--postdoctoral-researchers"><h2 class=mb-4>Postdoctoral Researchers</h2></div><div class="col-12 col-sm-auto people-person people-group--postdoctoral-researchers"><a href=/author/adrien-jolly/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/adrien-jolly/avatar_hu_1044d2f8d65faaab.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/adrien-jolly/>Adrien Jolly</a></h2><h3>Postdoctoral Researcher</h3><p class=people-interests>Blood cell development, Modeling of cell population dynamics in vivo, Omics data analysis, Immune cell repertoire analysis</p></div></div><div class="col-12 col-sm-auto people-person people-group--postdoctoral-researchers"><a href=/author/giuseppe-serra/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/giuseppe-serra/avatar_hu_20001565d1b1ec5a.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/giuseppe-serra/>Giuseppe Serra</a></h2><h3>Postdoctoral Researcher</h3><p class=people-interests>Machine Learning, Federated Continual Learning, Trustworthy and Explainable AI</p></div></div><div class="col-md-12 people-group--doctoral-researchers"><h2 class=mb-4>Doctoral Researchers</h2></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/arber-qoku/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/arber-qoku/avatar_hu_d4a7ecca809f4721.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/arber-qoku/>Arber Qoku</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Probabilistic Machine Learning, Multi-omics Data Integration, Survival Analysis</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/achim-hekler/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/achim-hekler/avatar_hu_407ebc6cc565cb6c.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/achim-hekler/>Achim Hekler</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Machine Learning, Trustworthy AI, Calibration, AI Beyond Benchmarks</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/sareh-ameri-far/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/sareh-ameri-far/avatar_hu_7ff7bfefc6e6043.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/sareh-ameri-far/>Sareh Ameri Far</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Multi-omics Data Analysis, Machine Learning, Oncology</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/tyra-stickel/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/tyra-stickel/avatar_hu_8235e81d85679f9a.JPG alt=Avatar></a><div class=portrait-title><h2><a href=/author/tyra-stickel/>Tyra Stickel</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Medical Data Analysis, Machine Learning, Multi-omics Data Integration</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/yihao-liu/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/yihao-liu/avatar_hu_dbf1de3f73b498b6.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/yihao-liu/>Yihao Liu</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Spatial Transcriptomics, Bone Marrow Microenvironment, Graph Theory</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/nassim-walha/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/nassim-walha/avatar_hu_387cff7138657ba8.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/nassim-walha/>Nassim Walha</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Generative AI, Uncertainty Quantification, Robustness, Privacy</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/dustin-eisenhardt/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/dustin-eisenhardt/avatar_hu_43e8fe651643027d.JPG alt=Avatar></a><div class=portrait-title><h2><a href=/author/dustin-eisenhardt/>Dustin Eisenhardt</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Deep Learning, Active Learning, Multimodal Learning</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/yusuf-berk-oruc/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/yusuf-berk-oruc/avatar_hu_5e8c8ba27f18498.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/yusuf-berk-oruc/>Yusuf Berk Oruc</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Multi-omics Data Integration, Computer Vision, Oncology</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/hendrik-mehrtens/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/hendrik-mehrtens/avatar_hu_672b5df16836d3be.jpeg alt=Avatar></a><div class=portrait-title><h2><a href=/author/hendrik-mehrtens/>Hendrik Mehrtens</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Uncertainty Estimation, Probabilistic Machine Learning, Causal Machine Learning</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/azza-jenane/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/azza-jenane/avatar_hu_5dad3f294bd3de9a.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/azza-jenane/>Azza Jenane</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Large Language Models, Uncertainty Quantification, Trustworthy AI</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/rashika-jakhmola/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/rashika-jakhmola/avatar_hu_be6cb286d4fdf3bd.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/rashika-jakhmola/>Rashika Jakhmola</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Probabilistic Machine Learning, Representation Learning, Multi-omics data integration</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/leo-luty/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/leo-luty/avatar_hu_9e45bbe6cc434a0a.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/leo-luty/>Leo Lüty</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Multi-omics Data Integration, Spatial Transcriptomics, Oncology</p></div></div><div class="col-12 col-sm-auto people-person people-group--doctoral-researchers"><a href=/author/ana-maria-gomez-martinez/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/ana-maria-gomez-martinez/avatar_hu_c49c520a24aff329.png alt=Avatar></a><div class=portrait-title><h2><a href=/author/ana-maria-gomez-martinez/>Ana María Gómez Martínez</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Multi-omics Data Analysis, Machine Learning, Personalized Oncology</p></div></div><div class="col-md-12 people-group--staff-scientists"><h2 class=mb-4>Staff Scientists</h2></div><div class="col-12 col-sm-auto people-person people-group--staff-scientists"><a href=/author/ali-yavuz-cak%C4%B1r/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/ali-yavuz-cak%C4%B1r/avatar_hu_daf98fbc257ffec7.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/ali-yavuz-cak%C4%B1r/>Ali Yavuz Çakır</a></h2><h3>Research Scientist</h3><p class=people-interests>Next Generation Sequencing Systems, Bioinformatics, Data Science, Human Genetics</p></div></div><div class="col-12 col-sm-auto people-person people-group--staff-scientists"><a href=/author/lukas-kuhn/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/lukas-kuhn/avatar_hu_b275929a162046c2.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/lukas-kuhn/>Lukas Kuhn</a></h2><h3>Staff Scientist</h3><p class=people-interests>Multimodal Representation Learning, Predictive World Models, Self-Supervised Learning</p></div></div><div class="col-md-12 people-group--alumni"><h2 class=mb-4>Alumni</h2></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/andreas-kopf/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/andreas-kopf/avatar_hu_6a25e46d6e540cf8.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/andreas-kopf/>Andreas Kopf</a></h2><h3>Guest Scientist</h3><p class=people-interests>Machine Learning (ML), Deep Learning, Probabilistic Modeling</p></div></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/helong-gary-zhao/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/helong-gary-zhao/avatar_hu_5b1326eadd41ea66.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/helong-gary-zhao/>Helong Gary Zhao</a></h2><h3>Visiting Scientist</h3><p class=people-interests>Hematological malignancies, Clonal hematopoiesis, Precision Oncology, Cancer Prevention</p></div></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/sebastian-gruber/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/sebastian-gruber/avatar_hu_89a8ad82095d6219.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/sebastian-gruber/>Sebastian Gruber</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Calibration, Loss functions, Uncertainty Quantification</p></div></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/zahra-moslehi/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/zahra-moslehi/avatar_hu_44eb12882b1e49fe.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/zahra-moslehi/>Zahra Moslehi</a></h2><h3>Postdoctoral Researcher</h3><p class=people-interests>Machine learning, Bioinformatics, Probabilistic modeling, Metric learning, Omics data analysis</p></div></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/sarmad-ahmad-khan/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/sarmad-ahmad-khan/avatar_hu_f9440cd2373ef158.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/sarmad-ahmad-khan/>Sarmad Ahmad Khan</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Bioinformatics, Machine Learning, Oncological Studies, Calibration</p></div></div><div class="col-12 col-sm-auto people-person people-group--alumni"><a href=/author/kevin-de-azevedo/><img width=270 height=270 loading=lazy class="avatar avatar-circle" src=/author/kevin-de-azevedo/avatar_hu_4ab6548b41811b9b.jpg alt=Avatar></a><div class=portrait-title><h2><a href=/author/kevin-de-azevedo/>Kevin De Azevedo</a></h2><h3>Ph.D. Candidate</h3><p class=people-interests>Bioinformatics, Omics Data Analysis, Machine Learning, Multi-omics Data Integration</p></div></div></div></div></section><section id=teaching class="home-section wg-markdown"><div class=home-section-bg></div><div class=container><div class="row justify-content-center"><div class="section-heading col-12 mb-3 text-center"><h1 class=mb-0>Teaching</h1></div><div class=col-12><p>In the summer term 2025 we offer <a href="https://qis.server.uni-frankfurt.de/qisserver/rds?state=verpublish&status=init&vmfile=no&publishid=395547&moduleCall=webInfo&publishConfFile=webInfo&publishSubDir=veranstaltung" target=_blank rel=noopener>Introduction to AI</a>.</p><p>In the winter term 2025/2026 we offer a seminar on <a href="https://qis.server.uni-frankfurt.de/qisserver/rds?state=verpublish&status=init&vmfile=no&moduleCall=webInfo&publishConfFile=webInfo&publishSubDir=veranstaltung&veranstaltung.veranstid=411284" target=_blank rel=noopener>AI in Medicine</a>.</p></div></div></div></section><section id=jobs class="home-section wg-markdown"><div class=home-section-bg></div><div 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