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Introduction to Genetics and Bioinformatics

Isaac Pope edited this page Feb 27, 2026 · 2 revisions

this note is under construction*

General bioinformatics resources https://doi.org/10.1093/brain/awz295 https://doi.org/10.1038/s41588-019-0385-z https://doi.org/10.1016/j.biopsych.2020.05.022

A course on methods for imaging genetics https://warwick.ac.uk/fac/sci/statistics/staff/academic-research/nichols/presentations/ohbm2014/imggen

Review on genetics of brain connectivity: https://pubmed.ncbi.nlm.nih.gov/34508898/

Nonlinear mapping of AHBA coordinates Package: https://github.com/chrisgorgo/alleninf Coords: https://github.com/chrisgorgo/alleninf/blob/master/alleninf/data/corrected_mni_coordinates.csv

Spatial transcriptomics Brief introduction to different methods: https://t.co/EfFz0gDx4D

Workflow for scRNAseq analysis https://satijalab.org/seurat/articles/spatial_vignette.html

Introductory reviews: https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-022-01075-1

https://genome.cshlp.org/content/31/10/1706

https://www.nature.com/articles/s41592-022-01409-2

https://www.nature.com/articles/s41587-021-01182-1

https://www.nature.com/articles/s41467-021-25557-9

Datasets and other resources: https://docs.google.com/spreadsheets/d/1sJDb9B7AtYmfKv4-m8XR7uc3XXw_k4kGSout8cqZ8bY/edit#gid=1363594152 Benchmarking of different methods: https://twitter.com/sanjusinha7/status/1578434020643205120?s=43&t=4Xlp8-6biPf9Ykb36VBmOw

https://www.sciencedirect.com/science/article/pii/S1672022922000845

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-022-01075-1

Using the Allen atlas https://pubmed.ncbi.nlm.nih.gov/22996553/ https://pubmed.ncbi.nlm.nih.gov/30455082/ https://pubmed.ncbi.nlm.nih.gov/36324650/ https://pubmed.ncbi.nlm.nih.gov/30648605/ https://pubmed.ncbi.nlm.nih.gov/34783653/ https://pubmed.ncbi.nlm.nih.gov/36725139/

Heritability

A nice review article: https://doi.org/10.1038/s41562-023-01609-6

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