ProteinGym/config.json at main · OpenProteinAI/ProteinGym · GitHub

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{
    "PG_data_location": "~/.cache/proteingym",
    "model_list_zero_shot_substitutions_DMS":{
        "Site_Independent":{"input_score_name":"prediction_independent", "location":"EVmutation", "directionality": 1, "key": "mutant", "model_type":"MSA"},
        "EVmutation":{"input_score_name":"prediction_epistatic", "location":"EVmutation", "directionality": 1, "key": "mutant", "model_type":"MSA"},
        "DeepSequence_single":{"input_score_name":"evol_indices_seed_1000", "location":"DeepSequence", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "DeepSequence_ensemble":{"input_score_name":"evol_indices_ensemble", "location":"DeepSequence", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "EVE_single":{"input_score_name":"evol_indices_seed_1000", "location":"EVE", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "EVE_ensemble":{"input_score_name":"evol_indices_ensemble", "location":"EVE", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "Unirep":{"input_score_name":"Unirep_score", "location":"UniRep", "directionality": -1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Unirep_evotune":{"input_score_name":"Unirep_score", "location":"UniRep_evotuned", "directionality": -1, "key": "mutated_sequence","model_type":"MSA"},
        "MSA_Transformer_single":{"input_score_name":"esm_msa1b_t12_100M_UR50S_seed1", "location":"MSA_Transformer", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "MSA_Transformer_ensemble":{"input_score_name":"esm_msa1b_t12_100M_UR50S_ensemble", "location":"MSA_Transformer", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "ESM1b":{"input_score_name":"esm1b_t33_650M_UR50S", "location":"ESM1b", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM1v_single":{"input_score_name":"esm1v_t33_650M_UR90S_1", "location":"ESM1v", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM1v_ensemble":{"input_score_name":"Ensemble_ESM1v", "location":"ESM1v", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_8M":{"input_score_name":"esm2_t6_8M_UR50D", "location":"ESM2/8M", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_35M":{"input_score_name":"esm2_t12_35M_UR50D", "location":"ESM2/35M", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_150M":{"input_score_name":"esm2_t30_150M_UR50D", "location":"ESM2/150M", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_650M":{"input_score_name":"esm2_t33_650M_UR50D", "location":"ESM2/650M", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_3B":{"input_score_name":"esm2_t36_3B_UR50D", "location":"ESM2/3B", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ESM2_15B":{"input_score_name":"esm2_t48_15B_UR50D", "location":"ESM2/15B", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Wavenet":{"input_score_name":"Wavenet_prediction", "location":"Wavenet", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "RITA_s":{"input_score_name":"RITA_score", "location":"RITA/small", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_m":{"input_score_name":"RITA_score", "location":"RITA/medium", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_l":{"input_score_name":"RITA_score", "location":"RITA/large", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_xl":{"input_score_name":"RITA_score", "location":"RITA/xlarge", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_small":{"input_score_name":"Progen2_score", "location":"Progen2/small", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_medium":{"input_score_name":"Progen2_score", "location":"Progen2/medium", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_base":{"input_score_name":"Progen2_score", "location":"Progen2/base", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_large":{"input_score_name":"Progen2_score", "location":"Progen2/large", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_xlarge":{"input_score_name":"Progen2_score", "location":"Progen2/xlarge", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "GEMME":{"input_score_name":"GEMME_score", "location":"GEMME", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "VESPA":{"input_score_name":"VESPA", "location":"VESPA", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "VESPAl":{"input_score_name":"VESPAl", "location":"VESPA", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "VespaG":{"input_score_name":"VespaG", "location":"VespaG", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ProtGPT2":{"input_score_name":"ProtGPT2_score", "location":"ProtGPT2", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_S_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_S", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_M_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_L_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_S":{"input_score_name":"avg_score", "location":"Tranception/Tranception_S", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Tranception_M":{"input_score_name":"avg_score", "location":"Tranception/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Tranception_L":{"input_score_name":"avg_score", "location":"Tranception/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "TranceptEVE_S":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_S", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "TranceptEVE_M":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_M", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "TranceptEVE_L":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_L", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "CARP_38M": {"input_score_name":"carp_38M_score","location":"CARP/carp_38M","directionality":1,"key":"mutant","model_type":"Single sequence"},
        "CARP_600K": {"input_score_name":"carp_600k_score","location":"CARP/carp_600k","directionality":1,"key":"mutant","model_type":"Single sequence"},
        "CARP_640M" : {"input_score_name":"carp_640M_score","location":"CARP/carp_640M","directionality":1,"key":"mutant","model_type":"Single sequence"},
        "CARP_76M": {"input_score_name":"carp_76M_score","location":"CARP/carp_76M","directionality":1,"key":"mutant","model_type":"Single sequence"},
        "MIF": {"input_score_name": "mif_score","location":"MIF/mif","directionality":1,"key":"mutant","model_type":"Structure"},
        "MIFST":{ "input_score_name": "mifst_score","location":"MIF/mifst","directionality":1,"key":"mutant","model_type":"Single sequence & Structure"},
        "ESM-IF1": {"input_score_name": "esmif1_ll","location":"ESM-IF1","directionality":1,"key":"mutant","model_type":"Structure"},
        "ProteinMPNN": {"input_score_name": "pmpnn_ll","location":"ProteinMPNN","directionality":1,"key":"mutant","model_type":"Structure"},
        "ProtSSN_k10_h512":{"input_score_name":"ProtSSN_k10_h512", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k10_h768":{"input_score_name":"ProtSSN_k10_h768", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k10_h1280":{"input_score_name":"ProtSSN_k10_h1280", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k20_h512":{"input_score_name":"ProtSSN_k20_h512", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k20_h768":{"input_score_name":"ProtSSN_k20_h768", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k20_h1280":{"input_score_name":"ProtSSN_k20_h1280", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k30_h512":{"input_score_name":"ProtSSN_k30_h512", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k30_h768":{"input_score_name":"ProtSSN_k30_h768", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_k30_h1280":{"input_score_name":"ProtSSN_k30_h1280", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProtSSN_ensemble":{"input_score_name":"ProtSSN_ensemble", "location":"ProtSSN", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "SaProt_650M_AF2":{"input_score_name":"SaProt_score", "location":"SaProt/SaProt_650M_AF2", "directionality": 1, "key": "mutant", "model_type":"Single sequence & Structure"},
        "SaProt_35M_AF2":{"input_score_name":"SaProt_score", "location":"SaProt/SaProt_35M_AF2", "directionality": 1, "key": "mutant", "model_type":"Single sequence & Structure"},
        "PoET": {"input_score_name": "PoET_score","location":"PoET","directionality":1,"key":"mutated_sequence","model_type":"MSA"},
        "MULAN_small":{"input_score_name":"MULAN_score", "location":"MULAN/MULAN_small", "directionality": 1, "key": "mutant", "model_type":"Single sequence & Structure"},
        "ProSST-20":{"input_score_name":"ProSST-20", "location":"ProSST/ProSST-20", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProSST-128":{"input_score_name":"ProSST-128", "location":"ProSST/ProSST-128", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProSST-512":{"input_score_name":"ProSST-512", "location":"ProSST/ProSST-512", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProSST-1024":{"input_score_name":"ProSST-1024", "location":"ProSST/ProSST-1024", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProSST-2048":{"input_score_name":"ProSST-2048", "location":"ProSST/ProSST-2048", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ProSST-4096":{"input_score_name":"ProSST-4096", "location":"ProSST/ProSST-4096", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "ESCOTT":{"input_score_name":"ESCOTT_score", "location":"ESCOTT", "directionality": 1, "key": "mutant","model_type":"Structure & MSA"},
        "VenusREM":{"input_score_name":"VenusREM", "location":"VenusREM", "directionality": 1, "key": "mutant","model_type":"Structure & MSA"},
        "RSALOR":{"input_score_name":"RSALOR", "location":"RSALOR", "directionality": -1, "key": "mutant","model_type":"Structure & MSA"},
        "S2F":{"input_score_name":"s2f_score", "location":"S2F", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "S2F_MSA":{"input_score_name":"s2f_MSA_score", "location":"S2F", "directionality": 1, "key": "mutant","model_type":"Structure & MSA"},
        "S3F":{"input_score_name":"s3f_score", "location":"S3F", "directionality": 1, "key": "mutant","model_type":"Single sequence & Structure"},
        "S3F_MSA":{"input_score_name":"s3f_MSA_score", "location":"S3F", "directionality": 1, "key": "mutant","model_type":"Structure & MSA"},
        "SiteRM":{"input_score_name":"SiteRM_score", "location":"SiteRM", "directionality": 1, "key": "mutant", "model_type":"MSA"},
        "ESM3":{"input_score_name":"ESM3_open_score", "location":"ESM3", "directionality": 1, "key": "mutant", "model_type":"Single sequence, Structure & Function annotations"},
        "ESMC-300M":{"input_score_name":"esmc_300M_score", "location":"ESM_C/300M", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "ESMC-600M":{"input_score_name":"esmc_600M_score", "location":"ESM_C/600M", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-1B-MLM":{"input_score_name":"proteinglm-1b-mlm_mlm_score", "location":"xTrimoPGLM/proteinglm-1b-mlm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-3B-MLM":{"input_score_name":"proteinglm-3b-mlm_mlm_score", "location":"xTrimoPGLM/proteinglm-3b-mlm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-10B-MLM":{"input_score_name":"proteinglm-10b-mlm_mlm_score", "location":"xTrimoPGLM/proteinglm-10b-mlm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-1B-CLM":{"input_score_name":"proteinglm-1b-clm_clm_score", "location":"xTrimoPGLM/proteinglm-1b-clm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-3B-CLM":{"input_score_name":"proteinglm-3b-clm_clm_score", "location":"xTrimoPGLM/proteinglm-3b-clm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-7B-CLM":{"input_score_name":"proteinglm-7b-clm_clm_score", "location":"xTrimoPGLM/proteinglm-7b-clm", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "xTrimoPGLM-100B-int4":{"input_score_name":"proteinglm-100b-int4_mlm_score", "location":"xTrimoPGLM/proteinglm-100b-int4", "directionality": 1, "key": "mutant", "model_type":"Single sequence"},
        "Progen3_112m":{"input_score_name":"log_likelihood", "location":"Progen3/112m", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen3_219m":{"input_score_name":"log_likelihood", "location":"Progen3/219m", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen3_339m":{"input_score_name":"log_likelihood", "location":"Progen3/339m", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen3_762m":{"input_score_name":"log_likelihood", "location":"Progen3/762m", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen3_1b":{"input_score_name":"log_likelihood", "location":"Progen3/1b", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen3_3b":{"input_score_name":"log_likelihood", "location":"Progen3/3b", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "AIDO.Protein-RAG-16B":{"input_score_name":"AIDO.Protein-RAG-16B-zeroshot", "location":"AIDO/AIDO.Protein-RAG-16B", "directionality": 1, "key": "mutant","model_type":"Structure & MSA"},
        "Protriever":{"input_score_name":"likelihood", "location":"Protriever", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"}
    },
    "model_list_zero_shot_indels_DMS":{
        "Unirep":{"input_score_name":"Unirep_score", "location":"UniRep", "directionality": -1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Wavenet":{"input_score_name":"Wavenet_prediction", "location":"Wavenet", "directionality": -1, "key": "mutated_sequence","model_type":"MSA"},
        "RITA_s":{"input_score_name":"RITA_score", "location":"RITA/small", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_m":{"input_score_name":"RITA_score", "location":"RITA/medium", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_l":{"input_score_name":"RITA_score", "location":"RITA/large", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "RITA_xl":{"input_score_name":"RITA_score", "location":"RITA/xlarge", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_small":{"input_score_name":"Progen2_score", "location":"Progen2/small", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_medium":{"input_score_name":"Progen2_score", "location":"Progen2/medium", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_base":{"input_score_name":"Progen2_score", "location":"Progen2/base", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_large":{"input_score_name":"Progen2_score", "location":"Progen2/large", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "Progen2_xlarge":{"input_score_name":"Progen2_score", "location":"Progen2/xlarge", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "ProtGPT2":{"input_score_name":"ProtGPT2_score", "location":"ProtGPT2", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_S_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_S", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_M_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_L_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_S":{"input_score_name":"avg_score", "location":"Tranception/Tranception_S", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Tranception_M":{"input_score_name":"avg_score", "location":"Tranception/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Tranception_L":{"input_score_name":"avg_score", "location":"Tranception/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "TranceptEVE_S":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_S", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "TranceptEVE_M":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_M", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "TranceptEVE_L":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_L", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "HMM":{"input_score_name":"logprob", "location":"HMM", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "Provean":{"input_score_name":"Provean_score","location":"Provean","directionality":1,"key":"mutant","model_type":"MSA"},
        "PoET": {"input_score_name": "PoET_score","location":"PoET","directionality":1,"key":"mutated_sequence","model_type":"MSA"}
    },
    "model_list_zero_shot_indels_clinical":{
        "HMM":{"input_score_name":"logprob", "location":"HMM", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Progen2_small":{"input_score_name":"Progen2_score", "location":"Progen2/small", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Progen2_medium":{"input_score_name":"Progen2_score", "location":"Progen2/medium", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Progen2_base":{"input_score_name":"Progen2_score", "location":"Progen2/base", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Progen2_large":{"input_score_name":"Progen2_score", "location":"Progen2/large", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Progen2_xlarge":{"input_score_name":"Progen2_score", "location":"Progen2/xlarge", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "ProtGPT2":{"input_score_name":"ProtGPT2_score", "location":"ProtGPT2", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Provean":{"input_score_name":"provean_score","location":"Provean","directionality":1,"key":"mutated_sequence","model_type":"MSA"},
        "RITA_s":{"input_score_name":"RITA_score", "location":"RITA/small", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "RITA_m":{"input_score_name":"RITA_score", "location":"RITA/medium", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "RITA_l":{"input_score_name":"RITA_score", "location":"RITA/large", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "RITA_xl":{"input_score_name":"RITA_score", "location":"RITA/xlarge", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_M_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_L_no_retrieval":{"input_score_name":"avg_score", "location":"Tranception_no_retrieval/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"Single sequence"},
        "Tranception_M":{"input_score_name":"avg_score", "location":"Tranception/Tranception_M", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Tranception_L":{"input_score_name":"avg_score", "location":"Tranception/Tranception_L", "directionality": 1, "key": "mutated_sequence","model_type":"MSA"},
        "Unirep":{"input_score_name":"Unirep_score", "location":"Unirep", "directionality": -1, "key": "mutated_sequence","model_type":"Single sequence"},
        "PoET": {"input_score_name": "PoET_score","location":"PoET","directionality":-1,"key":"mutated_sequence","model_type":"MSA"}
    },
    "model_list_zero_shot_substitutions_clinical":{
        "ClinPred":{"input_score_name":"ClinPred_score", "location":"ClinPred", "directionality": 1, "key": "mutant","model_type":"Clinical Predictor"},
        "DANN":{"input_score_name":"DANN_score", "location":"DANN", "directionality": 1, "key": "mutant","model_type":"Clinical Predictor"},
        "MutationTaster":{"input_score_name":"MutationTaster_converted_rankscore","location":"MutationTaster","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "CADD":{"input_score_name":"CADD_phred","location":"CADD","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "FATHMM":{"input_score_name":"FATHMM_score","location":"FATHMM","directionality":-1,"key":"mutant","model_type":"Clinical Predictor"},
        "LRT":{"input_score_name":"LRT_score","location":"LRT","directionality":-1,"key":"mutant","model_type":"Clinical Predictor"},
        "LIST-S2":{"input_score_name":"LIST-S2_score","location":"LIST-S2","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "PrimateAI":{"input_score_name":"PrimateAI_score","location":"PrimateAI","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "MutPred":{"input_score_name":"MutPred_score","location":"MutPred","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "MutationAssessor":{"input_score_name":"MutationAssessor_score","location":"MutationAssessor","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "SIFT4G":{"input_score_name":"SIFT4G_score","location":"SIFT4G","directionality":-1,"key":"mutant","model_type":"Clinical Predictor"},
        "SIFT":{"input_score_name":"SIFT_score","location":"SIFT","directionality":-1,"key":"mutant","model_type":"Clinical Predictor"},
        "PolyPhen2 (HDIV)":{ "input_score_name":"Polyphen2_HDIV_score","location":"Polyphen2_HDIV","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "MPC":{"input_score_name":"MPC_score","location":"MPC","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "Provean":{"input_score_name":"PROVEAN_score","location":"PROVEAN","directionality":-1,"key":"mutant","model_type":"Clinical Predictor"},
        "DEOGEN2":{"input_score_name":"DEOGEN2_score","location":"DEOGEN2","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "PolyPhen2 (HVAR)":{"input_score_name":"Polyphen2_HVAR_score","location":"Polyphen2_HVAR","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "gMVP":{"input_score_name":"gMVP_score","location":"gMVP","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "VARITY (R)":{ "input_score_name":"VARITY_R_LOO_score","location":"VARITY_R_LOO","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "VARITY (ER)":{ "input_score_name":"VARITY_ER_LOO_score","location":"VARITY_ER_LOO","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "BayesDel (addAF)":{ "input_score_name":"BayesDel_addAF_score","location":"BayesDel_addAF","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "BayesDel (noAF)":{ "input_score_name":"BayesDel_noAF_score","location":"BayesDel_noAF","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "REVEL":{"input_score_name":"REVEL_score","location":"REVEL","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "VEST4":{"input_score_name":"VEST4_score","location":"VEST4","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "MetaRNN":{"input_score_name":"MetaRNN_score","location":"MetaRNN","directionality":1,"key":"mutant","model_type":"Clinical Predictor"},
        "TranceptEVE_L":{"input_score_name":"avg_score", "location":"TranceptEVE/TranceptEVE_L", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "GEMME":{"input_score_name":"GEMME_score", "location":"GEMME", "directionality": 1, "key": "mutant","model_type":"MSA"},
        "EVE":{"input_score_name":"EVE_evol_index", "location":"EVE", "directionality": -1, "key": "mutant","model_type":"MSA"},
        "ESM1b":{"input_score_name":"esm1b_t33_650M_UR50S", "location":"ESM1b", "directionality": 1, "key": "mutant","model_type":"Single sequence"},
        "PoET": {"input_score_name": "PoET_score","location":"PoET","directionality":-1,"key":"mutated_sequence","model_type":"MSA"},
        "SiteRM":{"input_score_name":"SiteRM_score", "location":"SiteRM", "directionality": 1, "key": "mutant", "model_type":"MSA"}
    },
    "model_list_supervised_substitutions_DMS":{
        "OHE - Not augmented":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_not_augmented","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "OHE - Augmented - DeepSequence":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_DeepSequence","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "OHE - Augmented - ESM1v":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_ESM1v","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "OHE - Augmented - MSA Transformer":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_MSAT","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "OHE - Augmented - Tranception":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_Tranception","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "OHE - Augmented - TranceptEVE":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"OHE_TranceptEVE","key":"mutated_sequence", "model_type": "One-hot Encoding"},
        "Embeddings - Augmented - ESM1v":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"ESM1v","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "Embeddings - Augmented - MSA Transformer":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"MSA_Transformer","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "Embeddings - Augmented - Tranception":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"Tranception","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "ProteinNPT":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"ProteinNPT","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "Kermut":{"input_score_name":"y_pred", "label_name": "y", "location":"kermut", "key": "mutant", "model_type":"Structure & sequence embedding"}
    },
    "model_list_supervised_indels_DMS":{
        "Embeddings_ESM1v_indels":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"ESM1v","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "Embeddings_MSA_Transformer_indels":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"MSA_Transformer","key":"mutated_sequence", "model_type": "Sequence Embedding"},
        "Embeddings_Tranception_indels":{"input_score_name":"predictions_fitness", "label_name": "labels_fitness","location":"Tranception","key":"mutated_sequence", "model_type": "Sequence Embedding"}
    }
}