ProKinO

Home > PDBe-KB Annotations > ProKinO

ProKinO

This page provides a description of the annotations provided by this PDBe-KB Consortium Member. These annotations are available via public FTP, from the PDBe graph database, the PDBe graph API, and on the PDBe-KB aggregated views of proteins.

---

Basic Information

What is the FTP URL of the provided annotations (JSON format)?

ftp://ftp.ebi.ac.uk/pub/databases/pdbe-kb/annotations/ProKinO/

What is the URL of the data resource/software?

https://prokino.uga.edu

Who is the owner of the data resource/software?

Natarajan Kannan

What are the annotations provided?

Protein kinase information including hierarchy, relationships unifying sequence, structure, function, mutation and pathway

How regularly are these annotations updated?

Quarterly

---

Description of the data

Is there a "raw_score" provided? How to interpret it? Does it have a value range? Does it have a unit?

None

Is there a "confidence_score" provided? How to interpret it? Does it have a value range?

None

Is there a "confidence_level" provided? How is it decided?

The data contains only high confidence annotations.

Are there benchmarking datasets? Are they available publicly? If yes, what is the URL?

We have an ontology available for download: http://prokino.uga.edu/downloads.html

How are these annotations collected/generated?

We aggregate data from multiple sources such as reactome, uniprot, cancer.sanger.ac.uk, and kinase.com. Then convert those as triples to form an OWL ontology. Finally, we create various SPARQL queries to provide custom information.