diff --git a/qubes/backup.py b/qubes/backup.py
index a337c7721..55eff9f7f 100644
--- a/qubes/backup.py
+++ b/qubes/backup.py
@@ -455,9 +455,10 @@ def get_files_to_backup(self):
             home_dir = pwd.getpwnam(local_user).pw_dir
 
             # Checking if target is not user home directory in dom0
-            if self.target_dir in ["", "~"] or Path(
-                self.target_dir
-            ).is_relative_to(home_dir):
+            if self.target_vm == self.app.domains[0] and (
+                self.target_dir in ["", "~"]
+                or Path(self.target_dir).is_relative_to(home_dir)
+            ):
                 raise qubes.exc.QubesException(
                     "Can not backup dom0 home directory to itself!"
                 )
diff --git a/qubes/tests/integ/backup.py b/qubes/tests/integ/backup.py
index f902227fa..9ae0c1bb0 100644
--- a/qubes/tests/integ/backup.py
+++ b/qubes/tests/integ/backup.py
@@ -584,11 +584,15 @@ def test_101_backup_dom0_to_dom0_home(self):
         home_dir = pwd.getpwnam(local_user).pw_dir
         with self.assertRaises(qubes.exc.QubesException):
             self.make_backup(
-                [self.app.domains[0]], target=home_dir, expect_failure=True
+                [self.app.domains[0]],
+                target_vm=self.app.domains[0],
+                target=home_dir,
+                expect_failure=True,
             )
         with self.assertRaises(qubes.exc.QubesException):
             self.make_backup(
                 [self.app.domains[0]],
+                target_vm=self.app.domains[0],
                 target=os.path.join(home_dir, "somedir"),
                 expect_failure=True,
             )