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feat: add cellular succinate export via MCT proton symport #1039

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feat: add cellular succinate export via MCT proton symport #1039

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30a3a9f
feat: add cellular succinate export via MCT proton symport (#424)
edkerk Jul 11, 2026
1c3a69c
chore: add macaw test result
edkerk Jul 11, 2026
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2 changes: 1 addition & 1 deletion data/testResults/README.md
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Expand Up @@ -4,7 +4,7 @@ The file here contains results from the [MACAW](https://github.com/Devlin-Moyer/

The test results shown here were obtained by the GitHub Actions run in:

- **PR #1029** (MACAW)
- **PR #1039** (MACAW)
- **PR #973** (gene essentiality)

The results will be updated by any subsequent pull request. Summary results are shown as a comment in the corresponding pull request.
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1 change: 1 addition & 0 deletions data/testResults/macaw_results.csv
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Expand Up @@ -12876,3 +12876,4 @@ MAR20188,MAM01098m <=> MAM01098c,MAM01098c;MAM01098m,ok,ok,ok,N/A
MAR20189,MAM01329c + 2 MAM01824m + 5 MAM02039m --> MAM01328c + 2 MAM01826m + 4 MAM02039i,MAM01328c;MAM01329c,ok,ok,ok,N/A
MAR20190,MAM01329c + MAM02039c + MAM02553c --> MAM01328c + MAM02552c,MAM01328c;MAM01329c,ok,ok,ok,N/A
MAR20191,MAM01371m + MAM01974m + MAM02578m --> MAM01285m + MAM01975m + MAM02751m,ok,ok,ok,ok,N/A
MAR20192,MAM02039e + MAM02943e <=> MAM02039c + MAM02943c,ok,ok,ok,ok,N/A
14 changes: 14 additions & 0 deletions model/Human-GEM.yml
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Expand Up @@ -245971,6 +245971,20 @@
- references: "PMID:11080211;PMID:1356223;PMID:14583610;PMID:16213501;PMID:7595668;PMID:8838581;PMID:9053810"
- subsystem: "Alanine, aspartate and glutamate metabolism"
- confidence_score: 0
- !!omap
- id: "MAR20192"
- name: "succinate transport via proton symport"
- metabolites: !!omap
- MAM02039c: 1
- MAM02039e: -1
- MAM02943c: 1
- MAM02943e: -1
- lower_bound: -1000
- upper_bound: 1000
- gene_reaction_rule: "ENSG00000141526 or ENSG00000155380"
- references: "PMID:35363247"
- subsystem: "Transport reactions"
- confidence_score: 0
- genes:
- !!omap
- id: "ENSG00000000419"
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1 change: 1 addition & 0 deletions model/reactions.tsv
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Expand Up @@ -12876,3 +12876,4 @@ MAR20188 0
MAR20189 0
MAR20190 0
MAR20191 R00253 GLNS R00253C r0077 GLNS MNXR100024 HMR_3890 RCR10506 0 RHEA:16169 HMR_3890
MAR20192 0