diff --git a/packages/tdesign-uniapp/.changelog/pr-4500.md b/packages/tdesign-uniapp/.changelog/pr-4500.md
new file mode 100644
index 000000000..f0f4b2369
--- /dev/null
+++ b/packages/tdesign-uniapp/.changelog/pr-4500.md
@@ -0,0 +1,6 @@
+---
+pr_number: 4500
+contributor: betavs
+---
+
+- fix(Table): 修复列配置中的类名选项无效的问题 @betavs ([#4500](https://github.com/Tencent/tdesign-miniprogram/pull/4500))
diff --git a/packages/uniapp-components/table/table.vue b/packages/uniapp-components/table/table.vue
index 6cdfd3669..9c9576d87 100644
--- a/packages/uniapp-components/table/table.vue
+++ b/packages/uniapp-components/table/table.vue
@@ -295,12 +295,27 @@ export default {
         return styles.join('; ');
       },
 
+      getCustomClassName(className = '') {
+        const calcClassName = (name) => {
+          if (typeof name === 'function') {
+            return name() || '';
+          }
+          return name;
+        };
+
+        if (Array.isArray(className)) {
+          return className.map(calcClassName);
+        }
+        return [calcClassName(className)];
+      },
+
       getThClassName(col, colIndex) {
         const classes = [];
         if (col.colKey) classes.push(`${name}__th-${col.colKey}`);
         if (col.align && col.align !== 'left') classes.push(`${prefix}-align-${col.align}`);
         if (col.fixed === 'left') classes.push(`${name}__cell--fixed-left`);
         if (col.fixed === 'right') classes.push(`${name}__cell--fixed-right`);
+        if (col.className) classes.push(...this.getCustomClassName(col.className));
         if (colIndex === this.lastFixedLeftIndex) classes.push(`${name}__cell--fixed-left-last`);
         if (colIndex === this.firstFixedRightIndex) classes.push(`${name}__cell--fixed-right-first`);
         return classes.join(' ');