diff --git a/BUILD.bazel b/BUILD.bazel
index b4f57d942b..3cfe83b6ff 100644
--- a/BUILD.bazel
+++ b/BUILD.bazel
@@ -53,6 +53,9 @@ COPTS = [
 }) + select({
     "//bazel/config:brpc_with_asan": ["-fsanitize=address"],
     "//conditions:default": [""],
+}) + select({
+    "//bazel/config:brpc_with_no_pthread_mutex_hook": ["-DNO_PTHREAD_MUTEX_HOOK"],
+    "//conditions:default": [""],
 })
 
 LINKOPTS = [
diff --git a/bazel/config/BUILD.bazel b/bazel/config/BUILD.bazel
index 2c36be414e..594dc5133b 100644
--- a/bazel/config/BUILD.bazel
+++ b/bazel/config/BUILD.bazel
@@ -136,4 +136,10 @@ config_setting(
     define_values = {
         "with_bthread_tracer": "true",
     },
+)
+
+config_setting(
+    name = "brpc_with_no_pthread_mutex_hook",
+    define_values = {"BRPC_WITH_NO_PTHREAD_MUTEX_HOOK": "true"},
+    visibility = ["//visibility:public"],
 )
\ No newline at end of file