diff --git a/.cargo/mutants.toml b/.cargo/mutants.toml
new file mode 100644
index 0000000..3ed309f
--- /dev/null
+++ b/.cargo/mutants.toml
@@ -0,0 +1 @@
+profile = "mutants"
diff --git a/.github/workflows/mutations.yml b/.github/workflows/mutations.yml
new file mode 100644
index 0000000..e1a59d8
--- /dev/null
+++ b/.github/workflows/mutations.yml
@@ -0,0 +1,42 @@
+name: Test mutants
+
+permissions:
+  contents: read
+
+env:
+  CARGO_TERM_COLOR: always
+
+on:
+  push:
+    branches:
+      - main
+  pull_request:
+
+jobs:
+  incremental-mutants:
+    name: Incremental mutants test
+    runs-on: ubuntu-latest
+    if: github.event_name == 'pull_request'
+    steps:
+      - uses: actions/checkout@v4
+        with:
+          fetch-depth: 0
+      - name: Relative diff
+        run: |
+          git branch -av
+          git diff origin/${{ github.base_ref }}.. | tee git.diff
+      - name: Rust Cache
+        uses: Swatinem/rust-cache@v2
+      - name: Install Rust toolchain
+        uses: taiki-e/install-action@v2
+        with:
+          tool: cargo-mutants
+      - name: Mutants
+        run: |
+          cargo mutants --no-shuffle -vV --exclude "example-crates/**" --in-diff git.diff -- --all-targets
+      - name: Archive mutants.out
+        uses: actions/upload-artifact@v4
+        if: always()
+        with:
+          name: mutants-incremental.out
+          path: mutants.out
diff --git a/.gitignore b/.gitignore
index 5348570..f8ac0d2 100644
--- a/.gitignore
+++ b/.gitignore
@@ -17,3 +17,6 @@ Cargo.lock
 
 # Ignore media (should go into media branch)
 *.gif
+
+# Ignore cargo-mutants generated output
+/mutants.out*
diff --git a/Cargo.toml b/Cargo.toml
index 076aadb..6832a68 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -14,3 +14,8 @@ print_stderr = "deny"
 
 [workspace.lints.rust]
 unexpected_cfgs = { level = "warn", check-cfg = ['cfg(coverage,coverage_nightly)'] }
+
+[profile.mutants]
+inherits = "test"
+debug = "none"
+opt-level = 3