diff --git a/src/Microsoft.Data.Sqlite.Core/SqliteConnection.cs b/src/Microsoft.Data.Sqlite.Core/SqliteConnection.cs
index 3062c0f923c..4e7b17e5bbc 100644
--- a/src/Microsoft.Data.Sqlite.Core/SqliteConnection.cs
+++ b/src/Microsoft.Data.Sqlite.Core/SqliteConnection.cs
@@ -78,9 +78,13 @@ static SqliteConnection()
             {
                 currentAppData = appDataType?.GetRuntimeProperty("Current")?.GetValue(null);
             }
-            catch (TargetInvocationException)
+            catch (TargetInvocationException ex) when (IsNoPackageIdentityException(ex.InnerException))
             {
-                // Ignore "The process has no package identity."
+                // Ignore the unpackaged-app "no package identity" case; ApplicationData.Current is unavailable there.
+            }
+            catch (InvalidOperationException ex) when (IsNoPackageIdentityException(ex))
+            {
+                // Ignore the unpackaged-app "no package identity" case; ApplicationData.Current is unavailable there.
             }
 
             if (currentAppData != null)
@@ -104,6 +108,11 @@ static SqliteConnection()
         }
     }
 
+    private static bool IsNoPackageIdentityException(Exception? ex)
+        => (ex is InvalidOperationException or COMException)
+            && (ex.HResult == unchecked((int)0x80073D54) // APPMODEL_ERROR_NO_PACKAGE
+                || ex.HResult == unchecked((int)0x8000000D)); // E_ILLEGAL_STATE_CHANGE
+
     /// <summary>
     ///     Initializes a new instance of the <see cref="SqliteConnection" /> class.
     /// </summary>