diff --git a/src/glide/browser/base/content/browser.mts b/src/glide/browser/base/content/browser.mts
index 5ceadfb2..09c78973 100644
--- a/src/glide/browser/base/content/browser.mts
+++ b/src/glide/browser/base/content/browser.mts
@@ -100,6 +100,8 @@ class GlideBrowserClass {
     document!.addEventListener("keydown", this.#on_keydown.bind(this), true);
     document!.addEventListener("keypress", this.#on_keypress.bind(this), true);
     document!.addEventListener("keyup", this.#on_keyup.bind(this), true);
+    document!.addEventListener("mousedown", this.#on_mousedown.bind(this), true);
+    document!.addEventListener("wheel", this.#on_wheel.bind(this), true);
     window.addEventListener("MozDOMFullscreen:Entered", this.#on_fullscreen_enter.bind(this), true);
     window.addEventListener("MozDOMFullscreen:Exited", this.#on_fullscreen_exit.bind(this), true);
 
@@ -1790,6 +1792,41 @@ class GlideBrowserClass {
     }
   }
 
+  async #on_mousedown(event: MouseEvent) {
+    if ((event.target as any).$glide_hack_click_from_hint) {
+      return;
+    }
+    const has_partial = this.key_manager.has_partial_mapping;
+    if (!has_partial) {
+      return;
+    }
+    const mode = this.state.mode;
+    this._log.debug("mousedown event", "resetting key sequence");
+    this.key_manager.reset_sequence();
+    this.#display_keyseq([]);
+    this.#invoke_keystatechanged_autocmd({
+      mode,
+      sequence: [],
+      partial: false,
+    });
+  }
+
+  async #on_wheel(_event: WheelEvent) {
+    const has_partial = this.key_manager.has_partial_mapping;
+    if (!has_partial) {
+      return;
+    }
+    const mode = this.state.mode;
+    this._log.debug("scroll event", "resetting key sequence");
+    this.key_manager.reset_sequence();
+    this.#display_keyseq([]);
+    this.#invoke_keystatechanged_autocmd({
+      mode,
+      sequence: [],
+      partial: false,
+    });
+  }
+
   /**
    * Returns the Glide JSActor for the currently focused frame.
    *
diff --git a/src/glide/browser/base/content/test/mode/browser_keyseq_display.ts b/src/glide/browser/base/content/test/mode/browser_keyseq_display.ts
index 46a1912a..17d8b612 100644
--- a/src/glide/browser/base/content/test/mode/browser_keyseq_display.ts
+++ b/src/glide/browser/base/content/test/mode/browser_keyseq_display.ts
@@ -120,3 +120,40 @@ add_task(async function test_keyseq_display_without_toolbar_button() {
   // Restore the button for other tests
   document!.body!.appendChild(original_button!);
 });
+
+add_task(async function test_click_resets_partial_leader_sequence() {
+  await reload_config(function _() {});
+  await keys("<escape>");
+  await keys("<leader>");
+  await sleep_frames(2);
+  is(GlideBrowser.key_manager.has_partial_mapping, true, "Leader key should start partial sequence");
+  is(GlideBrowser.key_manager.current_sequence.join(""), "<Space>", "Sequence should contain space");
+
+  const body = document!.querySelector("body")!;
+  EventUtils.synthesizeMouse(body, 100, 100, {}, window);
+  await sleep_frames(2);
+  is(GlideBrowser.key_manager.has_partial_mapping, false, "Click should reset partial sequence");
+  is(GlideBrowser.key_manager.current_sequence.length, 0, "Sequence should be empty after click");
+});
+
+add_task(async function test_wheel_resets_partial_leader_sequence() {
+  await reload_config(function _() {});
+  await BrowserTestUtils.withNewTab(
+    "http://mochi.test:8888/browser/glide/browser/base/content/test/mode/key_test.html",
+    async () => {
+      await keys("<escape>");
+      GlideBrowser.key_manager.reset_sequence();
+      await keys("<leader>");
+      await sleep_frames(2);
+
+      is(GlideBrowser.key_manager.has_partial_mapping, true, "Leader key should start partial sequence");
+      EventUtils.synthesizeWheel(document!.querySelector("body")!, 100, 100, {
+        deltaY: 100,
+      }, window);
+      await sleep_frames(2);
+
+      is(GlideBrowser.key_manager.has_partial_mapping, false, "Wheel should reset partial sequence");
+      is(GlideBrowser.key_manager.current_sequence.length, 0, "Sequence should be empty after wheel");
+    },
+  );
+});