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21 | 21 | * additional nodes (connectors) required to preserve all pairwise distances |
22 | 22 | * that the seeds had in the original network. |
23 | 23 | * |
24 | | - * The tool was developed to support network-based functional discovery, |
25 | | - * especially in biological interactomes, and to complement conventional |
26 | | - * techniques such as community detection or Gene Ontology enrichment. |
| 24 | + * The tool is designed to support network-based structural and functional |
| 25 | + * analyses in arbitrary undirected graphs, and to complement conventional |
| 26 | + * techniques such as community detection or shortest-path analysis. |
27 | 27 | * BasicSpanner is implemented in C++ using the Qt framework and is available |
28 | 28 | * for Linux and Windows. |
29 | 29 | * |
|
107 | 107 | * distribution obtained from random seed sets of equal size provides a |
108 | 108 | * statistical measure of how closely related the chosen seeds are in the |
109 | 109 | * network. |
110 | | - * - Complement Gene Ontology and community analyses: basic networks can |
111 | | - * highlight functional associations that conventional enrichment |
112 | | - * techniques fail to detect and can point out inconsistencies or |
113 | | - * omissions in existing annotation databases. |
| 110 | + * - Complement community and enrichment analyses: basic networks can |
| 111 | + * highlight structural associations that conventional techniques fail to |
| 112 | + * detect and can point out inconsistencies or omissions in existing |
| 113 | + * annotations of the underlying network. |
114 | 114 | * - Detect graph inconsistencies: when a single seed dramatically increases |
115 | 115 | * the number of required connectors, it often indicates that the seed is |
116 | 116 | * poorly related to the rest or that the underlying graph contains |
117 | 117 | * missing or erroneous data. |
118 | 118 | * |
119 | | - * Although the reference application domain is the analysis of biological |
120 | | - * interactomes, the method is applicable to any undirected network. |
| 119 | + * The method is applicable to any undirected network regardless of domain. |
121 | 120 | * |
122 | 121 | * @section about_usage Usage |
123 | 122 | * |
|
140 | 139 | * |
141 | 140 | * If you use BasicSpanner in your work, please cite: |
142 | 141 | * |
143 | | - * Marin J, Marin I. Extreme graph simplification applied to functional |
144 | | - * discovery in biological networks (2026). |
| 142 | + * Marin J, Marin I. BasicSpanner. Zenodo (2026). |
| 143 | + * https://doi.org/10.5281/zenodo.19697430 |
145 | 144 | * |
146 | 145 | * @section about_license License |
147 | 146 | * |
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