linkml · cmungall · Jun 25, 2026 · Jun 25, 2026 · Jun 25, 2026 · Jun 25, 2026
diff --git a/cache/chmo/terms.csv b/cache/chmo/terms.csv
@@ -92,3 +92,13 @@ CHMO:0001477,crystallisation,2026-06-11T16:10:14.320283
 CHMO:0000158,powder X-ray diffraction,2026-06-11T16:10:21.908188
 CHMO:0000025,cyclic voltammetry,2026-06-11T16:10:31.974523
 CHMO:0002535,Karl–Fischer titration,2026-06-11T16:10:40.306624
+CHMO:0001532,distillation,2026-06-25T21:04:13.349577
+CHMO:0001681,leaching,2026-06-25T21:04:13.350319
+CHMO:0001641,micro-filtration,2026-06-25T21:04:14.116239
+CHMO:0001645,ultra-filtration,2026-06-25T21:04:14.117118
+CHMO:0001642,nano-filtration,2026-06-25T21:04:14.117843
+CHMO:0001643,reverse osmosis,2026-06-25T21:04:14.118535
+CHMO:0001624,fermentation,2026-06-25T21:04:16.308638
+CHMO:0001473,combustion,2026-06-25T21:04:16.309243
+CHMO:0001502,pyrolysis,2026-06-25T21:04:16.309789
+CHMO:0002231,purification,2026-06-25T21:04:16.310266
diff --git a/cache/obi/terms.csv b/cache/obi/terms.csv
@@ -82,3 +82,5 @@ OBI:0302886,centrifugation,2026-06-11T16:05:52.111915
 OBI:0000626,DNA sequencing assay,2026-06-11T16:09:55.501188
 OBI:0002107,bio-layer interferometry assay,2026-06-11T16:12:09.434877
 OBI:0000719,vaccine production,2026-06-23T05:48:33.992380
+OBI:0001046,bioreactor,2026-06-25T21:04:16.310785
+OBI:0000038,chromatography column,2026-06-25T21:04:16.311231
diff --git a/cache/uo/terms.csv b/cache/uo/terms.csv
@@ -69,3 +69,8 @@ UO:0000234,kilobyte,2025-10-19T07:20:52.384399
 UO:0000235,megabyte,2025-10-19T07:20:52.384574
 UO:0000164,mass volume percentage,2025-12-19T11:06:30.198413
 UO:0000165,volume percentage,2025-12-19T11:06:30.198991
+UO:0000112,joule,2026-06-25T21:27:03.811552
+UO:0000223,watt-hour,2026-06-25T21:27:03.812325
+UO:0000224,kilowatt-hour,2026-06-25T21:27:03.812954
+UO:0010051,large calorie,2026-06-25T21:27:03.813453
+UO:0000114,watt,2026-06-25T21:27:03.813962
diff --git a/src/valuesets/schema/bioprocessing/scale_up.yaml b/src/valuesets/schema/bioprocessing/scale_up.yaml
@@ -348,6 +348,40 @@ enums:
         description: Cell disruption/homogenization
         annotations:
           methods: High pressure, bead mill
+      CLARIFICATION:
+        description: Removal of cells and debris to produce a clarified harvest
+        annotations:
+          methods: Centrifugation, depth filtration
+      FLOCCULATION:
+        description: Aggregation of cells and debris into flocs to aid clarification
+      ULTRAFILTRATION:
+        title: ultra-filtration
+        description: Membrane concentration retaining macromolecules such as proteins
+        meaning: CHMO:0001645
+        annotations:
+          mwco: Typically 1-1000 kDa
+      DIAFILTRATION:
+        description: Buffer exchange and desalting by ultrafiltration with continuous makeup
+      TANGENTIAL_FLOW_FILTRATION:
+        description: Crossflow membrane filtration used for concentration and diafiltration
+        annotations:
+          aliases: TFF, crossflow filtration
+      BUFFER_EXCHANGE:
+        description: Replacement of the buffer matrix of a product stream
+      ADSORPTION:
+        description: Capture of product or impurities onto a solid sorbent
+      VIRAL_INACTIVATION:
+        description: Treatment step that inactivates potential viral contaminants
+        annotations:
+          methods: Low pH, solvent/detergent, heat
+      POLISHING:
+        description: Final chromatographic or filtration steps to remove trace impurities
+      LYOPHILIZATION:
+        title: freeze drying
+        description: Freeze-drying to produce a stable solid product
+        meaning: CHMO:0001553
+        annotations:
+          aliases: freeze drying
   FeedstockTypeEnum:
     title: Feedstock Type
     description: Types of feedstocks for bioprocessing

diff --git a/src/valuesets/schema/business/currencies.yaml b/src/valuesets/schema/business/currencies.yaml
@@ -0,0 +1,230 @@
+name: valuesets-business-currencies
+title: Currency Value Sets
+description: >-
+  Value set of world currencies identified by their ISO 4217 three-letter
+  alpha codes. Permissible value names are the ISO 4217 alpha-3 codes (an
+  existing standard) rather than upper-snake-case. Covers monetary fields such
+  as the PISCES Standard Flowsheet Format TEA_currency and per-mass price
+  units. This is a curated set of actively circulating currencies and is
+  extensible to the full ISO 4217 list.
+id: https://w3id.org/valuesets/business/currencies
+imports:
+- linkml:types
+prefixes:
+  linkml: https://w3id.org/linkml/
+  valuesets: https://w3id.org/valuesets/
+  orcid: https://orcid.org/
+  valuesets_meta: https://w3id.org/valuesets/meta/
+default_prefix: valuesets
+slots:
+  currency_code:
+    description: The ISO 4217 currency of a monetary amount
+    range: CurrencyCode
+enums:
+  CurrencyCode:
+    title: Currency Code
+    description: >-
+      World currencies by ISO 4217 alpha-3 code. The numeric_code, symbol, and
+      minor_unit (number of decimal places) annotations record the
+      corresponding ISO 4217 attributes.
+    status: DRAFT
+    contributors:
+    - orcid:0000-0002-6601-2165
+    - https://github.com/anthropics/claude-code
+    instantiates:
+    - valuesets_meta:ValueSetEnumDefinition
+    annotations:
+      standard: ISO 4217
+    permissible_values:
+      USD:
+        title: United States dollar
+        description: United States dollar
+        annotations: {numeric_code: '840', symbol: $, minor_unit: 2}
+      EUR:
+        title: Euro
+        description: Euro
+        annotations: {numeric_code: '978', symbol: "€", minor_unit: 2}
+      JPY:
+        title: Japanese yen
+        description: Japanese yen
+        annotations: {numeric_code: '392', symbol: "¥", minor_unit: 0}
+      GBP:
+        title: Pound sterling
+        description: British pound sterling
+        annotations: {numeric_code: '826', symbol: "£", minor_unit: 2}
+      CNY:
+        title: Renminbi
+        description: Chinese yuan renminbi
+        annotations: {numeric_code: '156', symbol: "¥", minor_unit: 2}
+      AUD:
+        title: Australian dollar
+        description: Australian dollar
+        annotations: {numeric_code: '036', symbol: $, minor_unit: 2}
+      CAD:
+        title: Canadian dollar
+        description: Canadian dollar
+        annotations: {numeric_code: '124', symbol: $, minor_unit: 2}
+      CHF:
+        title: Swiss franc
+        description: Swiss franc
+        annotations: {numeric_code: '756', symbol: Fr, minor_unit: 2}
+      HKD:
+        title: Hong Kong dollar
+        description: Hong Kong dollar
+        annotations: {numeric_code: '344', symbol: $, minor_unit: 2}
+      SGD:
+        title: Singapore dollar
+        description: Singapore dollar
+        annotations: {numeric_code: '702', symbol: $, minor_unit: 2}
+      SEK:
+        title: Swedish krona
+        description: Swedish krona
+        annotations: {numeric_code: '752', symbol: kr, minor_unit: 2}
+      NOK:
+        title: Norwegian krone
+        description: Norwegian krone
+        annotations: {numeric_code: '578', symbol: kr, minor_unit: 2}
+      DKK:
+        title: Danish krone
+        description: Danish krone
+        annotations: {numeric_code: '208', symbol: kr, minor_unit: 2}
+      NZD:
+        title: New Zealand dollar
+        description: New Zealand dollar
+        annotations: {numeric_code: '554', symbol: $, minor_unit: 2}
+      KRW:
+        title: South Korean won
+        description: South Korean won
+        annotations: {numeric_code: '410', symbol: "₩", minor_unit: 0}
+      INR:
+        title: Indian rupee
+        description: Indian rupee
+        annotations: {numeric_code: '356', symbol: "₹", minor_unit: 2}
+      BRL:
+        title: Brazilian real
+        description: Brazilian real
+        annotations: {numeric_code: '986', symbol: R$, minor_unit: 2}
+      ZAR:
+        title: South African rand
+        description: South African rand
+        annotations: {numeric_code: '710', symbol: R, minor_unit: 2}
+      RUB:
+        title: Russian ruble
+        description: Russian ruble
+        annotations: {numeric_code: '643', symbol: "₽", minor_unit: 2}
+      MXN:
+        title: Mexican peso
+        description: Mexican peso
+        annotations: {numeric_code: '484', symbol: $, minor_unit: 2}
+      TRY:
+        title: Turkish lira
+        description: Turkish lira
+        annotations: {numeric_code: '949', symbol: "₺", minor_unit: 2}
+      PLN:
+        title: Polish zloty
+        description: Polish zloty
+        annotations: {numeric_code: '985', symbol: "zł", minor_unit: 2}
+      THB:
+        title: Thai baht
+        description: Thai baht
+        annotations: {numeric_code: '764', symbol: "฿", minor_unit: 2}
+      IDR:
+        title: Indonesian rupiah
+        description: Indonesian rupiah
+        annotations: {numeric_code: '360', symbol: Rp, minor_unit: 2}
+      MYR:
+        title: Malaysian ringgit
+        description: Malaysian ringgit
+        annotations: {numeric_code: '458', symbol: RM, minor_unit: 2}
+      PHP:
+        title: Philippine peso
+        description: Philippine peso
+        annotations: {numeric_code: '608', symbol: "₱", minor_unit: 2}
+      AED:
+        title: UAE dirham
+        description: United Arab Emirates dirham
+        annotations: {numeric_code: '784', minor_unit: 2}
+      SAR:
+        title: Saudi riyal
+        description: Saudi riyal
+        annotations: {numeric_code: '682', minor_unit: 2}
+      ILS:
+        title: Israeli new shekel
+        description: Israeli new shekel
+        annotations: {numeric_code: '376', symbol: "₪", minor_unit: 2}
+      CZK:
+        title: Czech koruna
+        description: Czech koruna
+        annotations: {numeric_code: '203', symbol: "Kč", minor_unit: 2}
+      HUF:
+        title: Hungarian forint
+        description: Hungarian forint
+        annotations: {numeric_code: '348', symbol: Ft, minor_unit: 2}
+      RON:
+        title: Romanian leu
+        description: Romanian leu
+        annotations: {numeric_code: '946', symbol: lei, minor_unit: 2}
+      UAH:
+        title: Ukrainian hryvnia
+        description: Ukrainian hryvnia
+        annotations: {numeric_code: '980', symbol: "₴", minor_unit: 2}
+      CLP:
+        title: Chilean peso
+        description: Chilean peso
+        annotations: {numeric_code: '152', symbol: $, minor_unit: 0}
+      COP:
+        title: Colombian peso
+        description: Colombian peso
+        annotations: {numeric_code: '170', symbol: $, minor_unit: 2}
+      ARS:
+        title: Argentine peso
+        description: Argentine peso
+        annotations: {numeric_code: '032', symbol: $, minor_unit: 2}
+      EGP:
+        title: Egyptian pound
+        description: Egyptian pound
+        annotations: {numeric_code: '818', symbol: "£", minor_unit: 2}
+      NGN:
+        title: Nigerian naira
+        description: Nigerian naira
+        annotations: {numeric_code: '566', symbol: "₦", minor_unit: 2}
+      KES:
+        title: Kenyan shilling
+        description: Kenyan shilling
+        annotations: {numeric_code: '404', symbol: Sh, minor_unit: 2}
+      PKR:
+        title: Pakistani rupee
+        description: Pakistani rupee
+        annotations: {numeric_code: '586', symbol: "₨", minor_unit: 2}
+      BDT:
+        title: Bangladeshi taka
+        description: Bangladeshi taka
+        annotations: {numeric_code: '050', symbol: "৳", minor_unit: 2}
+      VND:
+        title: Vietnamese dong
+        description: Vietnamese dong
+        annotations: {numeric_code: '704', symbol: "₫", minor_unit: 0}
+      TWD:
+        title: New Taiwan dollar
+        description: New Taiwan dollar
+        annotations: {numeric_code: '901', symbol: $, minor_unit: 2}
+      KWD:
+        title: Kuwaiti dinar
+        description: Kuwaiti dinar
+        annotations: {numeric_code: '414', minor_unit: 3}
+      BHD:
+        title: Bahraini dinar
+        description: Bahraini dinar
+        annotations: {numeric_code: '048', minor_unit: 3}
+      OMR:
+        title: Omani rial
+        description: Omani rial
+        annotations: {numeric_code: '512', minor_unit: 3}
+      QAR:
+        title: Qatari riyal
+        description: Qatari riyal
+        annotations: {numeric_code: '634', minor_unit: 2}
+      ISK:
+        title: Icelandic krona
+        description: Icelandic krona
+        annotations: {numeric_code: '352', symbol: kr, minor_unit: 0}
diff --git a/src/valuesets/schema/chemistry/identifiers.yaml b/src/valuesets/schema/chemistry/identifiers.yaml
@@ -0,0 +1,64 @@
+name: valuesets-chemistry-identifiers
+title: Chemical Identifier Value Sets
+description: >-
+  Value sets for the identifier schemes used to reference chemical substances.
+  Covers fields such as the PISCES Standard Flowsheet Format chemical
+  registry_id ("CAS number or SMILES string").
+id: https://w3id.org/valuesets/chemistry/identifiers
+imports:
+- linkml:types
+prefixes:
+  linkml: https://w3id.org/linkml/
+  valuesets: https://w3id.org/valuesets/
+  orcid: https://orcid.org/
+  valuesets_meta: https://w3id.org/valuesets/meta/
+default_prefix: valuesets
+slots:
+  chemical_identifier_scheme:
+    description: The scheme/namespace of a chemical identifier
+    range: ChemicalIdentifierScheme
+enums:
+  ChemicalIdentifierScheme:
+    title: Chemical Identifier Scheme
+    description: >-
+      Schemes used to identify chemical substances, including registry numbers,
+      line notations, structure-derived keys, and database accessions.
+    status: DRAFT
+    contributors:
+    - orcid:0000-0002-6601-2165
+    - https://github.com/anthropics/claude-code
+    instantiates:
+    - valuesets_meta:ValueSetEnumDefinition
+    permissible_values:
+      CAS_RN:
+        description: CAS Registry Number assigned by the Chemical Abstracts Service
+        annotations:
+          example: 64-17-5
+      SMILES:
+        description: Simplified Molecular-Input Line-Entry System structure notation
+        annotations:
+          example: CCO
+      INCHI:
+        description: IUPAC International Chemical Identifier structure string
+        annotations:
+          example: InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
+      INCHIKEY:
+        description: Hashed fixed-length form of an InChI
+        annotations:
+          example: LFQSCWFLJHTTHZ-UHFFFAOYSA-N
+      IUPAC_NAME:
+        description: Systematic IUPAC chemical name
+      MOLECULAR_FORMULA:
+        description: Molecular or empirical chemical formula
+        annotations:
+          example: C2H6O
+      PUBCHEM_CID:
+        description: PubChem Compound Identifier
+      CHEBI_ID:
+        description: ChEBI ontology identifier
+      KEGG_COMPOUND:
+        description: KEGG COMPOUND database accession
+      DRUGBANK_ID:
+        description: DrugBank accession
+      EC_NUMBER:
+        description: European Community (EINECS/EC) substance number