diff --git a/marimo/_cli/sandbox.py b/marimo/_cli/sandbox.py
index c34da872498..d7c7f9e57c3 100644
--- a/marimo/_cli/sandbox.py
+++ b/marimo/_cli/sandbox.py
@@ -182,6 +182,24 @@ def include_features(dep: str, features: list[DepFeatures]) -> str:
     return filtered + [include_features(chosen, additional_features)]
 
 
+def _resolve_local_path_line(line: str, script_dir: Path) -> str:
+    """Resolve a relative local-path requirement to an absolute path.
+
+    >>> _resolve_local_path_line(
+    ...     "-e ../pkg ; py<'3.12' # via foo", Path("/a/b")
+    ... )
+    '-e /a/pkg ; py<\\'3.12\\' # via foo'
+    """
+    rest = line.removeprefix("-e ")
+    path_and_comment, _, _ = rest.partition(";")
+    path_token, _, _ = path_and_comment.partition(" #")
+    path_token = path_token.rstrip()
+    if not path_token.startswith("."):
+        return line
+    resolved = str((script_dir / path_token).resolve())
+    return line.replace(path_token, resolved, 1)
+
+
 def _uv_export_script_requirements_txt(
     name: str | None,
 ) -> list[str]:
@@ -202,7 +220,11 @@ def _uv_export_script_requirements_txt(
         capture_output=True,
         text=True,
     )
-    return result.stdout.split("\n")
+    script_dir = Path(name).resolve().parent
+    return [
+        _resolve_local_path_line(line, script_dir)
+        for line in result.stdout.split("\n")
+    ]
 
 
 def _resolve_requirements_txt_lines(pyproject: PyProjectReader) -> list[str]:
diff --git a/tests/_cli/test_sandbox.py b/tests/_cli/test_sandbox.py
index 0d781eee753..312ee22a21f 100644
--- a/tests/_cli/test_sandbox.py
+++ b/tests/_cli/test_sandbox.py
@@ -1,12 +1,10 @@
 from __future__ import annotations
 
 import os
-from typing import TYPE_CHECKING, Any
+from pathlib import Path
+from typing import Any
 from unittest.mock import patch
 
-if TYPE_CHECKING:
-    from pathlib import Path
-
 import pytest
 
 from marimo._cli.sandbox import (
@@ -845,3 +843,34 @@ def test_build_sandbox_venv_with_additional_deps(tmp_path: Path) -> None:
         assert os.path.exists(venv_python)
     finally:
         cleanup_sandbox_dir(sandbox_dir)
+
+
+def test_resolve_local_path_line() -> None:
+    from marimo._cli.sandbox import _resolve_local_path_line
+
+    d = Path("/project/notebooks")
+    _r = lambda p: str((d / p).resolve())  # noqa: E731
+
+    # Plain relative
+    assert _resolve_local_path_line("../../mylib", d) == _r("../../mylib")
+    # Editable
+    assert _resolve_local_path_line("-e ../pkg", d) == f"-e {_r('../pkg')}"
+    # Env marker
+    result = _resolve_local_path_line("../pkg ; py<'3.12'", d)
+    assert _r("../pkg") in result
+    assert "py<'3.12'" in result
+    # Inline comment
+    result = _resolve_local_path_line("../pkg # via foo", d)
+    assert _r("../pkg") in result
+    assert "# via foo" in result
+    # Both marker and comment
+    result = _resolve_local_path_line("../pkg ; py<'3.12' # via foo", d)
+    assert _r("../pkg") in result
+    assert "py<'3.12'" in result
+    assert "# via foo" in result
+    # Spaces in path
+    assert _r("../my lib") in _resolve_local_path_line("../my lib", d)
+    # Non-relative unchanged
+    assert _resolve_local_path_line("numpy==1.26.0", d) == "numpy==1.26.0"
+    assert _resolve_local_path_line("/absolute/path", d) == "/absolute/path"
+    assert _resolve_local_path_line("", d) == ""