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64 changes: 64 additions & 0 deletions CITATION.cff
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@@ -0,0 +1,64 @@
cff-version: "1.2.0"
authors:
- family-names: Allen
given-names: Joshua M.
orcid: "https://orcid.org/0009-0008-0002-5239"
- email: krg3@uic.edu
family-names: Gandhi
given-names: Keshav R.
orcid: "https://orcid.org/0009-0000-1718-1862"
- family-names: Alhazmy
given-names: Raghid
orcid: "https://orcid.org/0009-0005-6614-7050"
- family-names: Wasnik
given-names: Yash
orcid: "https://orcid.org/0009-0006-0108-7445"
- email: cfliege2@illinois.edu
family-names: Fliege
given-names: Christina E.
orcid: "https://orcid.org/0000-0001-8085-779X"
contact:
- email: krg3@uic.edu
family-names: Gandhi
given-names: Keshav R.
orcid: "https://orcid.org/0009-0000-1718-1862"
- email: cfliege2@illinois.edu
family-names: Fliege
given-names: Christina E.
orcid: "https://orcid.org/0000-0001-8085-779X"
doi: 10.5281/zenodo.19662441
message: If you use this software, please cite both the original publication of NEAT in PLOS One (2016) as well as our
article from the Journal of Open Source Software (2026). You can find both citations at the top of README.md, with
DOIs provided that link to the original papers.
preferred-citation:
authors:
- family-names: Allen
given-names: Joshua M.
orcid: "https://orcid.org/0009-0008-0002-5239"
- email: krg3@uic.edu
family-names: Gandhi
given-names: Keshav R.
orcid: "https://orcid.org/0009-0000-1718-1862"
- family-names: Alhazmy
given-names: Raghid
orcid: "https://orcid.org/0009-0005-6614-7050"
- family-names: Wasnik
given-names: Yash
orcid: "https://orcid.org/0009-0006-0108-7445"
- email: cfliege2@illinois.edu
family-names: Fliege
given-names: Christina E.
orcid: "https://orcid.org/0000-0001-8085-779X"
date-published: 2026-05-04
doi: 10.21105/joss.09056
issn: 2475-9066
issue: 121
journal: Journal of Open Source Software
publisher:
name: Open Journals
start: 9056
title: "Enhancing short-read sequencing simulation: Updates to NEAT"
type: article
url: "https://joss.theoj.org/papers/10.21105/joss.09056"
volume: 11
title: "Enhancing short-read sequencing simulation: Updates to NEAT"
8 changes: 6 additions & 2 deletions README.md
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Expand Up @@ -16,9 +16,13 @@ Developing and validating bioinformatics pipelines depends on access to genomic

NEAT is a fine-grained read simulator that simulates real-looking data using models learned from specific datasets. It was originally designed to simulate short reads and is adaptable to different machines, with custom error models and the capability to handle single-base substitutions, indel errors, and other types of mutations. Unlike simulators that rely solely on fixed error profiles, NEAT can learn empirical mutation and sequencing models from real datasets and use these models to generate realistic sequencing data, providing outputs in several common file formats (e.g., FASTQ, BAM, and VCF). There are several supporting utilities for generating models used for simulation and for comparing the outputs of alignment and variant calling to the golden BAM and golden VCF produced by NEAT.

To cite this work, please use:
To cite this work, please use both of the following:

> Stephens, Z. D., Hudson, M. E., Mainzer, L. S., Taschuk, M., Weber, M. R., & Iyer, R. K. (2016). Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models. _PLOS ONE_, _11_(11), e0167047. https://doi.org/10.1371/journal.pone.0167047
1. > Stephens, Z. D., Hudson, M. E., Mainzer, L. S., Taschuk, M., Weber, M. R., & Iyer, R. K. (2016). Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models. _PLOS ONE_, _11_(11), e0167047. https://doi.org/10.1371/journal.pone.0167047

2. > Allen, J. M., Gandhi, K. R., Alhazmy, R., Wasnik, Y., & Fliege, C. E. (2026). Enhancing next-generation sequencing simulation: Updates to NEAT. _Journal of Open Source Software_, _11_(121), 9056. https://doi.org/10.21105/joss.09056

[![DOI](https://joss.theoj.org/papers/10.21105/joss.09056/status.svg)](https://doi.org/10.21105/joss.09056)

## Table of Contents

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