diff --git a/lib/util/cache.js b/lib/util/cache.js
index 6f347936941..10b0d8afcbc 100644
--- a/lib/util/cache.js
+++ b/lib/util/cache.js
@@ -4,6 +4,8 @@ const {
   safeHTTPMethods
 } = require('../core/util')
 
+const { serializePathWithQuery } = require('../core/util')
+
 /**
  * @param {import('../../types/dispatcher.d.ts').default.DispatchOptions} opts
  */
@@ -12,10 +14,18 @@ function makeCacheKey (opts) {
     throw new Error('opts.origin is undefined')
   }
 
+  let fullPath
+  try {
+    fullPath = serializePathWithQuery(opts.path || '/', opts.query)
+  } catch (error) {
+    // If fails (path already has query params), use as-is
+    fullPath = opts.path || '/'
+  }
+
   return {
     origin: opts.origin.toString(),
     method: opts.method,
-    path: opts.path,
+    path: fullPath,
     headers: opts.headers
   }
 }
diff --git a/test/interceptors/cache-query-params.js b/test/interceptors/cache-query-params.js
new file mode 100644
index 00000000000..8ce7742b196
--- /dev/null
+++ b/test/interceptors/cache-query-params.js
@@ -0,0 +1,229 @@
+'use strict'
+
+const { test, after } = require('node:test')
+const { equal, notEqual } = require('node:assert')
+const { createServer } = require('node:http')
+const { once } = require('node:events')
+const { Client, request, interceptors } = require('../../')
+
+test('query parameters create separate cache entries', async () => {
+  let requestCount = 0
+  const server = createServer((req, res) => {
+    requestCount++
+    const url = new URL(req.url, 'http://localhost')
+    const param = url.searchParams.get('param') || 'default'
+
+    res.writeHead(200, {
+      'Content-Type': 'application/json',
+      'Cache-Control': 'public, max-age=100'
+    })
+    res.end(JSON.stringify({
+      message: `Response for param=${param}`,
+      requestNumber: requestCount
+    }))
+  })
+
+  server.listen(0)
+  await once(server, 'listening')
+
+  const client = new Client(`http://localhost:${server.address().port}`)
+    .compose(interceptors.cache())
+
+  after(async () => {
+    server.close()
+    await client.close()
+  })
+
+  const origin = `http://localhost:${server.address().port}`
+
+  // First request with param=value1
+  const response1 = await request(origin, {
+    dispatcher: client,
+    query: { param: 'value1' }
+  })
+  const body1 = await response1.body.text()
+  equal(requestCount, 1, 'First request should hit the server')
+
+  // Second request with same param - should be cached
+  const response2 = await request(origin, {
+    dispatcher: client,
+    query: { param: 'value1' }
+  })
+  const body2 = await response2.body.text()
+  equal(requestCount, 1, 'Second request with same query should be cached')
+  equal(body1, body2, 'Cached response should match original')
+
+  // Third request with different param - should NOT be cached
+  const response3 = await request(origin, {
+    dispatcher: client,
+    query: { param: 'value2' }
+  })
+  const body3 = await response3.body.text()
+  equal(requestCount, 2, 'Request with different query should hit the server')
+  notEqual(body1, body3, 'Different query parameters should create separate cache entries')
+})
+
+test('complex query parameters are handled correctly', async () => {
+  let requestCount = 0
+  const server = createServer((req, res) => {
+    requestCount++
+
+    res.writeHead(200, {
+      'Content-Type': 'application/json',
+      'Cache-Control': 'public, max-age=100'
+    })
+    res.end(JSON.stringify({
+      url: req.url,
+      requestNumber: requestCount
+    }))
+  })
+
+  server.listen(0)
+  await once(server, 'listening')
+
+  const client = new Client(`http://localhost:${server.address().port}`)
+    .compose(interceptors.cache())
+
+  after(async () => {
+    server.close()
+    await client.close()
+  })
+
+  const origin = `http://localhost:${server.address().port}`
+
+  // Complex query with arrays and multiple parameters
+  const complexQuery = {
+    search: 'hello world',
+    tags: ['javascript', 'nodejs'],
+    limit: 10,
+    active: true
+  }
+
+  // First request
+  const response1 = await request(origin, {
+    dispatcher: client,
+    query: complexQuery
+  })
+  const body1 = await response1.body.text()
+  equal(requestCount, 1, 'First complex query should hit the server')
+
+  // Same complex query - should be cached
+  const response2 = await request(origin, {
+    dispatcher: client,
+    query: complexQuery
+  })
+  const body2 = await response2.body.text()
+  equal(requestCount, 1, 'Same complex query should be cached')
+  equal(body1, body2, 'Complex query parameters should be cached correctly')
+
+  // Slightly different query - should NOT be cached
+  const response3 = await request(origin, {
+    dispatcher: client,
+    query: {
+      search: 'hello world',
+      tags: ['javascript', 'nodejs'],
+      limit: 20, // Different limit
+      active: true
+    }
+  })
+  const body3 = await response3.body.text()
+  equal(requestCount, 2, 'Different complex query should hit the server')
+  notEqual(body1, body3, 'Different query parameters should create separate cache entries')
+})
+
+test('query parameters vs path equivalence', async () => {
+  let requestCount = 0
+  const server = createServer((req, res) => {
+    requestCount++
+
+    res.writeHead(200, {
+      'Content-Type': 'application/json',
+      'Cache-Control': 'public, max-age=100'
+    })
+    res.end(JSON.stringify({
+      url: req.url,
+      requestNumber: requestCount
+    }))
+  })
+
+  server.listen(0)
+  await once(server, 'listening')
+
+  const client = new Client(`http://localhost:${server.address().port}`)
+    .compose(interceptors.cache())
+
+  after(async () => {
+    server.close()
+    await client.close()
+  })
+
+  const origin = `http://localhost:${server.address().port}`
+
+  // Request using query object
+  const response1 = await request(origin, {
+    dispatcher: client,
+    query: { foo: 'bar', baz: 'qux' }
+  })
+  const body1 = await response1.body.text()
+  equal(requestCount, 1, 'Query object request should hit the server')
+
+  // Request using path with query string - should be cached if URLs match
+  const response2 = await request(`${origin}/?foo=bar&baz=qux`, {
+    dispatcher: client
+  })
+  const body2 = await response2.body.text()
+  equal(requestCount, 1, 'Equivalent path query should be cached')
+  equal(body1, body2, 'Query object and path query should be equivalent')
+})
+
+test('empty and undefined query parameters', async () => {
+  let requestCount = 0
+  const server = createServer((req, res) => {
+    requestCount++
+
+    res.writeHead(200, {
+      'Content-Type': 'application/json',
+      'Cache-Control': 'public, max-age=100'
+    })
+    res.end(JSON.stringify({
+      url: req.url,
+      requestNumber: requestCount
+    }))
+  })
+
+  server.listen(0)
+  await once(server, 'listening')
+
+  const client = new Client(`http://localhost:${server.address().port}`)
+    .compose(interceptors.cache())
+
+  after(async () => {
+    server.close()
+    await client.close()
+  })
+
+  const origin = `http://localhost:${server.address().port}`
+
+  // Request with no query
+  const response1 = await request(origin, { dispatcher: client })
+  const body1 = await response1.body.text()
+  equal(requestCount, 1, 'No query request should hit the server')
+
+  // Request with empty query object - should be cached
+  const response2 = await request(origin, {
+    dispatcher: client,
+    query: {}
+  })
+  const body2 = await response2.body.text()
+  equal(requestCount, 1, 'Empty query object should be cached')
+  equal(body1, body2, 'No query and empty query should be equivalent')
+
+  // Request with undefined query - should be cached
+  const response3 = await request(origin, {
+    dispatcher: client,
+    query: undefined
+  })
+  const body3 = await response3.body.text()
+  equal(requestCount, 1, 'Undefined query should be cached')
+  equal(body1, body3, 'No query and undefined query should be equivalent')
+})