diff --git a/docs/how-to/react-server-components.md b/docs/how-to/react-server-components.md
index 6283213d99..0c410e1844 100644
--- a/docs/how-to/react-server-components.md
+++ b/docs/how-to/react-server-components.md
@@ -385,7 +385,6 @@ The following options from `react-router.config.ts` are not currently supported
 - `presets`
 - `serverBundles`
 - `splitRouteModules`
-- `subResourceIntegrity`
 
 ## RSC Data Mode
 
diff --git a/integration/sri-test.ts b/integration/sri-test.ts
index 3ccd26b153..ec2e00cd98 100644
--- a/integration/sri-test.ts
+++ b/integration/sri-test.ts
@@ -1,4 +1,7 @@
-import { test, expect } from "@playwright/test";
+import { createHash } from "node:crypto";
+import { readFile } from "node:fs/promises";
+import path from "node:path";
+import { expect } from "@playwright/test";
 
 import {
   createAppFixture,
@@ -6,10 +9,15 @@ import {
   js,
 } from "./helpers/create-fixture.js";
 import type { AppFixture, Fixture } from "./helpers/create-fixture.js";
-import { reactRouterConfig } from "./helpers/vite.js";
+import {
+  type Files,
+  reactRouterConfig,
+  test,
+  viteConfig,
+} from "./helpers/vite.js";
 import { PlaywrightFixture } from "./helpers/playwright-fixture.js";
 
-test.describe("CSub-Resource Integrity", () => {
+test.describe("Sub-Resource Integrity", () => {
   test.use({ javaScriptEnabled: false });
 
   let fixture: Fixture;
@@ -85,3 +93,67 @@ test.describe("CSub-Resource Integrity", () => {
     }
   });
 });
+
+test.describe("Sub-Resource Integrity in RSC Framework Mode (production)", () => {
+  test.use({ javaScriptEnabled: false });
+
+  let fixture: Fixture;
+  let appFixture: AppFixture;
+
+  test.beforeAll(async () => {
+    fixture = await createFixture({
+      templateName: "rsc-vite-framework",
+      files: {
+        "react-router.config.ts": reactRouterConfig({
+          subResourceIntegrity: true,
+        }),
+      },
+    });
+    appFixture = await createAppFixture(fixture);
+  });
+
+  test("includes an importmap with integrity hashes", async ({ page }) => {
+    let app = new PlaywrightFixture(appFixture, page);
+    await app.goto("/");
+    let json = await page.locator('script[type="importmap"]').innerText();
+    let importMap = JSON.parse(json);
+    expect(Object.keys(importMap.integrity).length).toBeGreaterThan(0);
+    for (let [url, value] of Object.entries(importMap.integrity)) {
+      expect(value).toMatch(/^sha384-/);
+
+      let asset = await readFile(
+        path.join(fixture.projectDir, "build/client", url),
+      );
+      let expected = `sha384-${createHash("sha384")
+        .update(asset)
+        .digest("base64")}`;
+      expect(value).toBe(expected);
+    }
+  });
+});
+
+test.describe("Sub-Resource Integrity in RSC Framework Mode (development)", () => {
+  test("accepts the config without emitting production integrity hashes", async ({
+    page,
+    dev,
+  }) => {
+    let files: Files = async ({ port }) => ({
+      "react-router.config.ts": reactRouterConfig({
+        subResourceIntegrity: true,
+      }),
+      "vite.config.ts": await viteConfig.basic({
+        port,
+        templateName: "rsc-vite-framework",
+      }),
+    });
+
+    let { port } = await dev(files, "rsc-vite-framework");
+
+    await page.goto(`http://localhost:${port}/`);
+    await expect(page.getByRole("heading")).toHaveText(
+      "Welcome to React Router",
+    );
+    await expect(page.locator('script[type="importmap"]')).toHaveCount(0);
+    expect(page.errors).toEqual([]);
+  });
+});
diff --git a/packages/react-router-dev/.changes/unstable.rsc-subresource-integrity.md b/packages/react-router-dev/.changes/unstable.rsc-subresource-integrity.md
new file mode 100644
index 0000000000..271c6e15d8
--- /dev/null
+++ b/packages/react-router-dev/.changes/unstable.rsc-subresource-integrity.md
@@ -0,0 +1,19 @@
+Support the `subResourceIntegrity` config option in RSC Framework Mode
+
+### Migration guide
+
+No changes are required when using the default RSC SSR entry. If you maintain a custom `app/entry.ssr.tsx`, import the new virtual module and pass its hashes to React's `importMap` render option:
+
+```diff
++import subResourceIntegrity from "virtual:react-router/unstable_rsc/subresource-integrity";
+
+return renderToReadableStream(<RSCStaticRouter getPayload={getPayload} />, {
+  ...options,
+  bootstrapScriptContent,
+  formState,
++ importMap: subResourceIntegrity
++   ? { integrity: subResourceIntegrity }
++   : undefined,
+  signal: request.signal,
+});
+```
diff --git a/packages/react-router-dev/config/default-rsc-entries/entry.ssr.tsx b/packages/react-router-dev/config/default-rsc-entries/entry.ssr.tsx
index c30c5acac9..18fa49a75e 100644
--- a/packages/react-router-dev/config/default-rsc-entries/entry.ssr.tsx
+++ b/packages/react-router-dev/config/default-rsc-entries/entry.ssr.tsx
@@ -4,6 +4,7 @@ import {
   unstable_routeRSCServerRequest as routeRSCServerRequest,
   unstable_RSCStaticRouter as RSCStaticRouter,
 } from "react-router";
+import subResourceIntegrity from "virtual:react-router/unstable_rsc/subresource-integrity";
 
 export async function generateHTML(
   request: Request,
@@ -31,6 +32,9 @@ export async function generateHTML(
           ...options,
           bootstrapScriptContent,
           formState,
+          importMap: subResourceIntegrity
+            ? { integrity: subResourceIntegrity }
+            : undefined,
           signal: request.signal,
         },
       );
diff --git a/packages/react-router-dev/rsc-types.d.ts b/packages/react-router-dev/rsc-types.d.ts
index 58223e68de..a9556ef55d 100644
--- a/packages/react-router-dev/rsc-types.d.ts
+++ b/packages/react-router-dev/rsc-types.d.ts
@@ -15,6 +15,11 @@ declare module "virtual:react-router/unstable_rsc/ssr" {
   export default ssr;
 }
 
+declare module "virtual:react-router/unstable_rsc/subresource-integrity" {
+  const subResourceIntegrity: Record<string, string> | undefined;
+  export default subResourceIntegrity;
+}
+
 declare module "virtual:react-router/unstable_rsc/react-router-serve-config" {
   const unstable_reactRouterServeConfig: {
     publicPath: string;
diff --git a/packages/react-router-dev/vite/rsc/plugin.ts b/packages/react-router-dev/vite/rsc/plugin.ts
index 8a7705bb81..b4463bc861 100644
--- a/packages/react-router-dev/vite/rsc/plugin.ts
+++ b/packages/react-router-dev/vite/rsc/plugin.ts
@@ -1,4 +1,5 @@
 import type * as Vite from "vite";
+import { createHash } from "node:crypto";
 import { init as initEsModuleLexer } from "es-module-lexer";
 import * as Path from "pathe";
 import colors from "picocolors";
@@ -161,8 +162,6 @@ export function reactRouterRSCVitePlugin(): Vite.PluginOption[] {
             if (userConfig.buildEnd) errors.push("buildEnd");
             if (userConfig.presets?.length) errors.push("presets");
             if (userConfig.serverBundles) errors.push("serverBundles");
-            if (userConfig.subResourceIntegrity)
-              errors.push("subResourceIntegrity");
             if (errors.length) {
               return `RSC Framework Mode does not currently support the following React Router config:\n${errors.map((x) => ` - ${x}`).join("\n")}\n`;
             }
@@ -512,6 +511,45 @@ export function reactRouterRSCVitePlugin(): Vite.PluginOption[] {
         }
       : null,
 
+    (() => {
+      let sri: Record<string, string> | undefined;
+
+      return {
+        name: "react-router/rsc/subresource-integrity",
+        sharedDuringBuild: true,
+        resolveId(id) {
+          if (id === virtual.subResourceIntegrity.id) {
+            return virtual.subResourceIntegrity.resolvedId;
+          }
+        },
+        load(id) {
+          if (id === virtual.subResourceIntegrity.resolvedId) {
+            return `export default ${JSON.stringify(sri)};`;
+          }
+        },
+        writeBundle(_options, bundle) {
+          if (
+            this.environment.name !== "client" ||
+            !config.subResourceIntegrity
+          ) {
+            return;
+          }
+
+          sri = {};
+          for (let output of Object.values(bundle)) {
+            if (!output.fileName.endsWith(".js")) {
+              continue;
+            }
+
+            let contents =
+              output.type === "chunk" ? output.code : output.source;
+            let hash = createHash("sha384").update(contents).digest("base64");
+            sri[`${resolvedViteConfig.base}${output.fileName}`] =
+              `sha384-${hash}`;
+          }
+        },
+      } satisfies Vite.Plugin;
+    })(),
     {
       name: "react-router/rsc/virtual-route-config",
       resolveId(id) {
@@ -781,6 +819,7 @@ export function reactRouterRSCVitePlugin(): Vite.PluginOption[] {
 
 const virtual = {
   routeConfig: create("unstable_rsc/routes"),
+  subResourceIntegrity: create("unstable_rsc/subresource-integrity"),
   routeDiscovery: create("unstable_rsc/route-discovery"),
   injectHmrRuntime: create("unstable_rsc/inject-hmr-runtime"),
   basename: create("unstable_rsc/basename"),