@@ -16,7 +16,7 @@ MBDoE analysis. This is in line with the convention used in the parameter estima
1616
1717An example of the subclassed :class: `Experiment ` object that builds and labels the model is shown in the next few sections.
1818
19- This guide illustrates the use of Pyomo.DoE using a reaction kinetics example (Wang and Dowling, 2022 ).
19+ This guide illustrates the use of Pyomo.DoE using a reaction kinetics example ([ WD22 ]_ ).
2020
2121.. math ::
2222 :nowrap:
@@ -117,17 +117,17 @@ Step 5: Exploratory analysis (Enumeration)
117117^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
118118
119119After creating the subclass of the :class: `Experiment ` class, exploratory analysis is
120- suggested to enumerate the design space to check if the problem is identifiable,
121- i.e., ensure that D-, E-optimality metrics are not small numbers near zero, and
122- Modified E-optimality is not a big number .
120+ suggested to systematically enumerate the experimental design space and identify regions
121+ that provide high information content about the model parameters, as quantified by
122+ the A-, D-, E-, and ME-optimality criteria .
123123Additionally, it helps to initialize the model for the optimal experimental design step.
124124
125- Pyomo.DoE can perform exploratory sensitivity analysis with the `` compute_FIM_full_factorial ` ` method.
126- The `` compute_FIM_full_factorial ` ` method generates a grid over the design space as specified by the user.
127- Each grid point represents an MBDoE problem solved using the `` compute_FIM ` ` method.
125+ Pyomo.DoE can perform exploratory sensitivity analysis with the :meth: ` compute_FIM_full_factorial ` method.
126+ The :meth: ` compute_FIM_full_factorial ` method generates a grid over the design space as specified by the user.
127+ Each grid point represents an MBDoE problem solved using the :meth: ` compute_FIM ` method.
128128In this way, sensitivity of the FIM over the design space can be evaluated.
129- Pyomo.DoE supports plotting the results from the `` compute_FIM_full_factorial ` ` method
130- with the `` draw_factorial_figure ` ` method.
129+ Pyomo.DoE supports plotting the results from the :meth: ` compute_FIM_full_factorial ` method
130+ with the :meth: ` draw_factorial_figure ` method.
131131
132132The following code defines the ``run_reactor_doe `` function. This function encapsulates
133133the workflow for both sensitivity analysis (Step 5) and optimal design (Step 6).
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