diff --git a/django/db/backends/base/features.py b/django/db/backends/base/features.py
index ecc283ff6ba5..1e957d105ed3 100644
--- a/django/db/backends/base/features.py
+++ b/django/db/backends/base/features.py
@@ -393,8 +393,10 @@ class BaseDatabaseFeatures:
     # subqueries?
     supports_tuple_comparison_against_subquery = True
 
-    # Does the backend support DEFAULT as delete option?
+    # Does the backend support CASCADE, DEFAULT, NULL as delete options?
+    supports_on_delete_db_cascade = True
     supports_on_delete_db_default = True
+    supports_on_delete_db_null = True
 
     # Collation names for use by the Django test suite.
     test_collations = {
diff --git a/django/db/models/expressions.py b/django/db/models/expressions.py
index 0d47366d2c03..6b90a42cf1d2 100644
--- a/django/db/models/expressions.py
+++ b/django/db/models/expressions.py
@@ -426,7 +426,7 @@ def replace_expressions(self, replacements):
         clone = self.copy()
         clone.set_source_expressions(
             [
-                expr.replace_expressions(replacements) if expr else None
+                None if expr is None else expr.replace_expressions(replacements)
                 for expr in source_expressions
             ]
         )
diff --git a/django/db/models/fields/related.py b/django/db/models/fields/related.py
index 0293c7890991..f1bc664007dd 100644
--- a/django/db/models/fields/related.py
+++ b/django/db/models/fields/related.py
@@ -12,6 +12,7 @@
 from django.db.models.constants import LOOKUP_SEP
 from django.db.models.deletion import (
     CASCADE,
+    DB_CASCADE,
     DB_SET_DEFAULT,
     DB_SET_NULL,
     DO_NOTHING,
@@ -1056,9 +1057,38 @@ def check(self, **kwargs):
             *self._check_unique(),
         ]
 
+    def _check_on_delete_db_support(self, on_delete, feature_flag, databases):
+        for db in databases:
+            if not router.allow_migrate_model(db, self.model):
+                continue
+            connection = connections[db]
+            if feature_flag in self.model._meta.required_db_features or getattr(
+                connection.features, feature_flag
+            ):
+                continue
+            no_db_option_name = on_delete.__name__.removeprefix("DB_")
+            yield checks.Error(
+                f"{connection.display_name} does not support a {on_delete.__name__}.",
+                hint=f"Change the on_delete rule to {no_db_option_name}.",
+                obj=self,
+                id="fields.E324",
+            )
+
     def _check_on_delete(self, databases):
         on_delete = getattr(self.remote_field, "on_delete", None)
         errors = []
+        if on_delete == DB_CASCADE:
+            errors.extend(
+                self._check_on_delete_db_support(
+                    on_delete, "supports_on_delete_db_cascade", databases
+                )
+            )
+        if on_delete == DB_SET_NULL:
+            errors.extend(
+                self._check_on_delete_db_support(
+                    on_delete, "supports_on_delete_db_null", databases
+                )
+            )
         if on_delete in [DB_SET_NULL, SET_NULL] and not self.null:
             errors.append(
                 checks.Error(
@@ -1092,25 +1122,12 @@ def _check_on_delete(self, databases):
                         id="fields.E322",
                     )
                 )
-            for db in databases:
-                if not router.allow_migrate_model(db, self.model):
-                    continue
-                connection = connections[db]
-                if not (
-                    "supports_on_delete_db_default"
-                    in self.model._meta.required_db_features
-                    or connection.features.supports_on_delete_db_default
-                ):
-                    errors.append(
-                        checks.Error(
-                            f"{connection.display_name} does not support a "
-                            "DB_SET_DEFAULT.",
-                            hint="Change the on_delete rule to SET_DEFAULT.",
-                            obj=self,
-                            id="fields.E324",
-                        ),
-                    )
-        elif not isinstance(self.remote_field.model, str) and on_delete != DO_NOTHING:
+            errors.extend(
+                self._check_on_delete_db_support(
+                    on_delete, "supports_on_delete_db_default", databases
+                )
+            )
+        if not isinstance(self.remote_field.model, str) and on_delete != DO_NOTHING:
             # Database and Python variants cannot be mixed in a chain of
             # model references.
             is_db_on_delete = isinstance(on_delete, DatabaseOnDelete)
diff --git a/docs/ref/checks.txt b/docs/ref/checks.txt
index 22ebfed2ca4e..7dfa7c61d24b 100644
--- a/docs/ref/checks.txt
+++ b/docs/ref/checks.txt
@@ -309,7 +309,8 @@ Related fields
   ``db_default`` value.
 * **fields.E323**: Field specifies database/Python-level on_delete variant, but
   referenced model uses python/database-level variant.
-* **fields.E324**: ``<database>`` does not support ``DB_SET_DEFAULT``.
+* **fields.E324**: ``<database>`` does not support
+  ``<database delete option>``.
 * **fields.E330**: ``ManyToManyField``\s cannot be unique.
 * **fields.E331**: Field specifies a many-to-many relation through model
   ``<model>``, which has not been installed.
diff --git a/docs/releases/5.2.9.txt b/docs/releases/5.2.9.txt
index 588c278be5e9..515b233b8a99 100644
--- a/docs/releases/5.2.9.txt
+++ b/docs/releases/5.2.9.txt
@@ -16,3 +16,7 @@ Bugfixes
 
 * Fixed a bug in Django 5.2 on PostgreSQL where ``bulk_create()`` did not apply
   a field's custom query placeholders (:ticket:`36748`).
+
+* Fixed a regression in Django 5.2.2 that caused a crash when using aggregate
+  functions with an empty ``Q`` filter over a queryset with annotations
+  (:ticket:`36751`).
diff --git a/tests/admin_utils/models.py b/tests/admin_utils/models.py
index e5d2b6788722..55810f0b50a8 100644
--- a/tests/admin_utils/models.py
+++ b/tests/admin_utils/models.py
@@ -55,6 +55,9 @@ class DBCascade(models.Model):
     def __str__(self):
         return str(self.num)
 
+    class Meta:
+        required_db_features = {"supports_on_delete_db_cascade"}
+
 
 class Event(models.Model):
     date = models.DateTimeField(auto_now_add=True)
diff --git a/tests/admin_utils/tests.py b/tests/admin_utils/tests.py
index ce32535c52f0..81c6f495f8ef 100644
--- a/tests/admin_utils/tests.py
+++ b/tests/admin_utils/tests.py
@@ -21,7 +21,7 @@
 from django.contrib.auth.templatetags.auth import render_password_as_hash
 from django.core.validators import EMPTY_VALUES
 from django.db import DEFAULT_DB_ALIAS, models
-from django.test import SimpleTestCase, TestCase, override_settings
+from django.test import SimpleTestCase, TestCase, override_settings, skipUnlessDBFeature
 from django.test.utils import isolate_apps
 from django.utils.formats import localize
 from django.utils.safestring import mark_safe
@@ -115,6 +115,7 @@ def test_relation_on_abstract(self):
         n.collect([Vehicle.objects.first()])
 
 
+@skipUnlessDBFeature("supports_on_delete_db_cascade")
 class DBNestedObjectsTests(NestedObjectsTests):
     """
     Exercise NestedObjectsTests but with a model that makes use of DB_CASCADE
diff --git a/tests/aggregation/test_filter_argument.py b/tests/aggregation/test_filter_argument.py
index 1a17703a8640..59588d30d05e 100644
--- a/tests/aggregation/test_filter_argument.py
+++ b/tests/aggregation/test_filter_argument.py
@@ -88,6 +88,17 @@ def test_empty_filtered_aggregates(self):
         agg = Count("pk", filter=Q())
         self.assertEqual(Author.objects.aggregate(count=agg)["count"], 3)
 
+    def test_empty_filtered_aggregates_with_annotation(self):
+        agg = Count("pk", filter=Q())
+        self.assertEqual(
+            Author.objects.annotate(
+                age_annotation=F("age"),
+            ).aggregate(
+                count=agg
+            )["count"],
+            3,
+        )
+
     def test_double_filtered_aggregates(self):
         agg = Sum("age", filter=Q(Q(name="test2") & ~Q(name="test")))
         self.assertEqual(Author.objects.aggregate(age=agg)["age"], 60)
diff --git a/tests/delete/models.py b/tests/delete/models.py
index bd9caf42a7ae..d8f81827be66 100644
--- a/tests/delete/models.py
+++ b/tests/delete/models.py
@@ -49,17 +49,26 @@ class RelatedDbOptionParent(models.Model):
     p = models.ForeignKey(RelatedDbOptionGrandParent, models.DB_CASCADE, null=True)
 
 
-class RelatedDbOption(models.Model):
+class CascadeDbModel(models.Model):
     name = models.CharField(max_length=30)
+    db_cascade = models.ForeignKey(
+        RelatedDbOptionParent, models.DB_CASCADE, related_name="db_cascade_set"
+    )
+
+    class Meta:
+        required_db_features = {"supports_on_delete_db_cascade"}
+
+
+class SetNullDbModel(models.Model):
     db_setnull = models.ForeignKey(
         RelatedDbOptionParent,
         models.DB_SET_NULL,
         null=True,
         related_name="db_setnull_set",
     )
-    db_cascade = models.ForeignKey(
-        RelatedDbOptionParent, models.DB_CASCADE, related_name="db_cascade_set"
-    )
+
+    class Meta:
+        required_db_features = {"supports_on_delete_db_null"}
 
 
 class SetDefaultDbModel(models.Model):
@@ -159,15 +168,6 @@ def create_a(name):
     return a
 
 
-def create_related_db_option(name):
-    a = RelatedDbOption(name=name)
-    for name in ["db_setnull", "db_cascade"]:
-        r = RelatedDbOptionParent.objects.create()
-        setattr(a, name, r)
-    a.save()
-    return a
-
-
 class M(models.Model):
     m2m = models.ManyToManyField(R, related_name="m_set")
     m2m_through = models.ManyToManyField(R, through="MR", related_name="m_through_set")
diff --git a/tests/delete/tests.py b/tests/delete/tests.py
index 8d525d1e5ff3..664cdfb440f2 100644
--- a/tests/delete/tests.py
+++ b/tests/delete/tests.py
@@ -15,6 +15,7 @@
     Avatar,
     B,
     Base,
+    CascadeDbModel,
     Child,
     DeleteBottom,
     DeleteTop,
@@ -34,16 +35,15 @@
     RChild,
     RChildChild,
     Referrer,
-    RelatedDbOption,
     RelatedDbOptionGrandParent,
     RelatedDbOptionParent,
     RProxy,
     S,
     SetDefaultDbModel,
+    SetNullDbModel,
     T,
     User,
     create_a,
-    create_related_db_option,
     get_default_r,
 )
 
@@ -81,10 +81,13 @@ def test_setnull(self):
         a = A.objects.get(pk=a.pk)
         self.assertIsNone(a.setnull)
 
+    @skipUnlessDBFeature("supports_on_delete_db_null")
     def test_db_setnull(self):
-        a = create_related_db_option("db_setnull")
+        a = SetNullDbModel.objects.create(
+            db_setnull=RelatedDbOptionParent.objects.create()
+        )
         a.db_setnull.delete()
-        a = RelatedDbOption.objects.get(pk=a.pk)
+        a = SetNullDbModel.objects.get(pk=a.pk)
         self.assertIsNone(a.db_setnull)
 
     def test_setdefault(self):
@@ -394,20 +397,21 @@ def test_bulk(self):
         self.assertNumQueries(5, s.delete)
         self.assertFalse(S.objects.exists())
 
+    @skipUnlessDBFeature("supports_on_delete_db_cascade")
     def test_db_cascade(self):
         related_db_op = RelatedDbOptionParent.objects.create(
             p=RelatedDbOptionGrandParent.objects.create()
         )
-        RelatedDbOption.objects.bulk_create(
+        CascadeDbModel.objects.bulk_create(
             [
-                RelatedDbOption(db_cascade=related_db_op)
+                CascadeDbModel(db_cascade=related_db_op)
                 for _ in range(2 * GET_ITERATOR_CHUNK_SIZE)
             ]
         )
         with self.assertNumQueries(1):
             results = related_db_op.delete()
             self.assertEqual(results, (1, {"delete.RelatedDbOptionParent": 1}))
-        self.assertFalse(RelatedDbOption.objects.exists())
+        self.assertFalse(CascadeDbModel.objects.exists())
         self.assertFalse(RelatedDbOptionParent.objects.exists())
 
     def test_instance_update(self):
diff --git a/tests/expressions/tests.py b/tests/expressions/tests.py
index 6f18321aa7b3..981d84e9e8ec 100644
--- a/tests/expressions/tests.py
+++ b/tests/expressions/tests.py
@@ -1571,6 +1571,24 @@ def test_get_expression_for_validation_only_one_source_expression(self):
         with self.assertRaisesMessage(ValueError, msg):
             expression.get_expression_for_validation()
 
+    def test_replace_expressions_falsey(self):
+        class AssignableExpression(Expression):
+            def __init__(self, *source_expressions):
+                super().__init__()
+                self.set_source_expressions(list(source_expressions))
+
+            def get_source_expressions(self):
+                return self.source_expressions
+
+            def set_source_expressions(self, exprs):
+                self.source_expressions = exprs
+
+        expression = AssignableExpression()
+        falsey = Q()
+        expression.set_source_expressions([falsey])
+        replaced = expression.replace_expressions({"replacement": Expression()})
+        self.assertEqual(replaced.get_source_expressions(), [falsey])
+
 
 class ExpressionsNumericTests(TestCase):
     @classmethod
diff --git a/tests/inspectdb/models.py b/tests/inspectdb/models.py
index fbe1df8a9531..489704879f35 100644
--- a/tests/inspectdb/models.py
+++ b/tests/inspectdb/models.py
@@ -178,3 +178,9 @@ class DbOnDeleteModel(models.Model):
     fk_set_null = models.ForeignKey(
         DigitsInColumnName, on_delete=models.DB_SET_NULL, null=True
     )
+
+    class Meta:
+        required_db_features = {
+            "supports_on_delete_db_cascade",
+            "supports_on_delete_db_null",
+        }
diff --git a/tests/inspectdb/tests.py b/tests/inspectdb/tests.py
index c16258b0eb67..8175c52e4ec9 100644
--- a/tests/inspectdb/tests.py
+++ b/tests/inspectdb/tests.py
@@ -301,7 +301,11 @@ def test_foreign_key_to_field(self):
             out.getvalue(),
         )
 
-    @skipUnlessDBFeature("can_introspect_foreign_keys")
+    @skipUnlessDBFeature(
+        "can_introspect_foreign_keys",
+        "supports_on_delete_db_cascade",
+        "supports_on_delete_db_null",
+    )
     def test_foreign_key_db_on_delete(self):
         out = StringIO()
         call_command("inspectdb", "inspectdb_dbondeletemodel", stdout=out)
diff --git a/tests/introspection/models.py b/tests/introspection/models.py
index 6c94f5212c9d..8ced619b08b2 100644
--- a/tests/introspection/models.py
+++ b/tests/introspection/models.py
@@ -112,11 +112,20 @@ class Meta:
         required_db_features = {"supports_comments"}
 
 
-class DbOnDeleteModel(models.Model):
+class DbOnDeleteCascadeModel(models.Model):
     fk_do_nothing = models.ForeignKey(Country, on_delete=models.DO_NOTHING)
     fk_db_cascade = models.ForeignKey(City, on_delete=models.DB_CASCADE)
+
+    class Meta:
+        required_db_features = {"supports_on_delete_db_cascade"}
+
+
+class DbOnDeleteSetNullModel(models.Model):
     fk_set_null = models.ForeignKey(Reporter, on_delete=models.DB_SET_NULL, null=True)
 
+    class Meta:
+        required_db_features = {"supports_on_delete_db_null"}
+
 
 class DbOnDeleteSetDefaultModel(models.Model):
     fk_db_set_default = models.ForeignKey(
diff --git a/tests/introspection/tests.py b/tests/introspection/tests.py
index 1f7f22b2dc16..3a2c6112c874 100644
--- a/tests/introspection/tests.py
+++ b/tests/introspection/tests.py
@@ -10,8 +10,9 @@
     Comment,
     Country,
     DbCommentModel,
-    DbOnDeleteModel,
+    DbOnDeleteCascadeModel,
     DbOnDeleteSetDefaultModel,
+    DbOnDeleteSetNullModel,
     District,
     Reporter,
     UniqueConstraintConditionModel,
@@ -244,11 +245,11 @@ def test_get_relations(self):
             editor.add_field(Article, body)
         self.assertEqual(relations, expected_relations)
 
-    @skipUnlessDBFeature("can_introspect_foreign_keys")
-    def test_get_relations_db_on_delete(self):
+    @skipUnlessDBFeature("can_introspect_foreign_keys", "supports_on_delete_db_cascade")
+    def test_get_relations_db_on_delete_cascade(self):
         with connection.cursor() as cursor:
             relations = connection.introspection.get_relations(
-                cursor, DbOnDeleteModel._meta.db_table
+                cursor, DbOnDeleteCascadeModel._meta.db_table
             )
 
         if connection.vendor == "mysql" and connection.mysql_is_mariadb:
@@ -259,6 +260,18 @@ def test_get_relations_db_on_delete(self):
         expected_relations = {
             "fk_db_cascade_id": ("id", City._meta.db_table, DB_CASCADE),
             "fk_do_nothing_id": ("id", Country._meta.db_table, no_db_on_delete),
+        }
+        self.assertEqual(relations, expected_relations)
+
+    @skipUnlessDBFeature("can_introspect_foreign_keys", "supports_on_delete_db_null")
+    def test_get_relations_db_on_delete_null(self):
+        with connection.cursor() as cursor:
+            relations = connection.introspection.get_relations(
+                cursor, DbOnDeleteSetNullModel._meta.db_table
+            )
+
+        # {field_name: (field_name_other_table, other_table, db_on_delete)}
+        expected_relations = {
             "fk_set_null_id": ("id", Reporter._meta.db_table, DB_SET_NULL),
         }
         self.assertEqual(relations, expected_relations)
diff --git a/tests/invalid_models_tests/test_relative_fields.py b/tests/invalid_models_tests/test_relative_fields.py
index e73f22ab41fe..51b1de149427 100644
--- a/tests/invalid_models_tests/test_relative_fields.py
+++ b/tests/invalid_models_tests/test_relative_fields.py
@@ -2288,6 +2288,41 @@ class FooBar(models.Model):
 @isolate_apps("invalid_models_tests")
 class DatabaseLevelOnDeleteTests(TestCase):
 
+    def test_db_cascade_support(self):
+        class Parent(models.Model):
+            pass
+
+        class Child(models.Model):
+            parent = models.ForeignKey(Parent, models.DB_CASCADE)
+
+        field = Child._meta.get_field("parent")
+        expected = (
+            []
+            if connection.features.supports_on_delete_db_cascade
+            else [
+                Error(
+                    f"{connection.display_name} does not support a DB_CASCADE.",
+                    hint="Change the on_delete rule to CASCADE.",
+                    obj=field,
+                    id="fields.E324",
+                )
+            ]
+        )
+        self.assertEqual(field.check(databases=self.databases), expected)
+
+    def test_db_cascade_required_db_features(self):
+        class Parent(models.Model):
+            pass
+
+        class Child(models.Model):
+            parent = models.ForeignKey(Parent, models.DB_CASCADE)
+
+            class Meta:
+                required_db_features = {"supports_on_delete_db_cascade"}
+
+        field = Child._meta.get_field("parent")
+        self.assertEqual(field.check(databases=self.databases), [])
+
     def test_db_set_default_support(self):
         class Parent(models.Model):
             pass
@@ -2349,6 +2384,41 @@ class Child(models.Model):
             ],
         )
 
+    def test_db_set_null_support(self):
+        class Parent(models.Model):
+            pass
+
+        class Child(models.Model):
+            parent = models.ForeignKey(Parent, models.DB_SET_NULL, null=True)
+
+        field = Child._meta.get_field("parent")
+        expected = (
+            []
+            if connection.features.supports_on_delete_db_null
+            else [
+                Error(
+                    f"{connection.display_name} does not support a DB_SET_NULL.",
+                    hint="Change the on_delete rule to SET_NULL.",
+                    obj=field,
+                    id="fields.E324",
+                )
+            ]
+        )
+        self.assertEqual(field.check(databases=self.databases), expected)
+
+    def test_db_set_null_required_db_features(self):
+        class Parent(models.Model):
+            pass
+
+        class Child(models.Model):
+            parent = models.ForeignKey(Parent, models.DB_SET_NULL, null=True)
+
+            class Meta:
+                required_db_features = {"supports_on_delete_db_null"}
+
+        field = Child._meta.get_field("parent")
+        self.assertEqual(field.check(databases=self.databases), [])
+
     def test_python_db_chain(self):
         class GrandParent(models.Model):
             pass
@@ -2376,6 +2446,7 @@ class Child(models.Model):
             ],
         )
 
+    @skipUnlessDBFeature("supports_on_delete_db_null")
     def test_db_python_chain(self):
         class GrandParent(models.Model):
             pass
@@ -2403,6 +2474,7 @@ class Child(models.Model):
             ],
         )
 
+    @skipUnlessDBFeature("supports_on_delete_db_cascade")
     def test_db_python_chain_auto_created(self):
         class GrandParent(models.Model):
             pass
@@ -2430,6 +2502,7 @@ class Child(models.Model):
             ],
         )
 
+    @skipUnlessDBFeature("supports_on_delete_db_null")
     def test_db_do_nothing_chain(self):
         class GrandParent(models.Model):
             pass