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<html lang="en">
<head>
<meta charset="UTF-8" />
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<meta http-equiv="X-UA-Compatible" content="ie=edge" />
<title>阿宾的BLOG</title>
<link rel="shortcut icon" href="https://xiaobin-phd.github.io/favicon.ico" />
<link
href="https://unpkg.com/remixicon@2.2.0/fonts/remixicon.css"
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<link
rel="alternate"
type="application/atom+xml"
title="阿宾的BLOG - Atom Feed"
href="https://xiaobin-phd.github.io/atom.xml" />
<meta name="description" content="" />
</head>
<body>
<div class="antialiased flex flex-col min-h-screen" id="app">
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class="nav py-3 md:py-8 fixed w-full z-10 bg-gray-50 dark:bg-gray-700 transition-all duration-300"
:class="{ 'scroll': scrolled }">
<div class="flex justify-end px-4">
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class="w-8 h-8 flex justify-center items-center rounded-full md:hidden"
@click="showMenu = !showMenu">
<i class="ri-close-line" v-show="showMenu"></i>
<i class="ri-menu-3-line" v-show="!showMenu"></i>
</div>
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class="max-w-4xl w-full mx-auto text-center flex flex-col md:flex-row justify-center md:block"
:class="`${ showMenu ? 'block' : 'hidden' }`">
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href="https://xiaobin-phd.github.io/atom.xml"
target="_blank"
class="py-2 md:py-1 px-4 mx-4 inline-flex transition font-semibold rounded dark:hover:bg-gray-600 hover:bg-gray-200">
RSS
</a>
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</div>
<div
class="max-w-4xl w-full mx-auto ">
<header
class="flex py-16 md:py-32 mt-12 flex-col md:flex-row px-4 md:px-0 animated fadeIn">
<div class="flex-1 order-2 md:order-1 md:pr-16">
<div class="text-4xl font-bold text-center md:text-left">
阿宾的BLOG
</div>
<div class="text-xl text-gray-500 mt-4 text-center md:text-left">
</div>
<div class="mt-8 flex items-center">
<div class="text-gray-500 mr-2">在这里找到我吧！</div>
<a
href="mailto:xiaobin-phd@gmail.com"
target="_blank"
class="mr-2 w-8 h-8 inline-flex items-center justify-center text-xl hover:bg-gray-200 dark:hover:bg-gray-600 transition-fast">
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href="https://github.com/xiaobin-phd"
target="_blank"
class="mr-2 w-8 h-8 inline-flex items-center justify-center text-xl hover:bg-gray-200 dark:hover:bg-gray-600 transition-fast">
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</a>
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href="https://www.zhihu.com/people/bin-blog"
target="_blank"
class="mr-2 w-8 h-8 inline-flex items-center justify-center text-xl hover:bg-gray-200 dark:hover:bg-gray-600 transition-fast">
<i class="ri-zhihu-line"></i>
</a>
</div>
</div>
<div
class="md:mx-8 flex-shrink-0 self-start rounded-full border-4 border-dotted border-transparent hover:border-yellow-50 p-2 w-32 h-32 order-1 md:order-2 mx-auto s3-dotted">
<img
class="rounded-full object-cover"
src="https://xiaobin-phd.github.io/images/avatar.png?v=1730597578109"
alt="阿宾的BLOG"
width="100%"
height="100%" />
</div>
</header>
<div
class="shadow-box bg-white dark:bg-gray-600 border-gray-300 rounded-none md:rounded-lg -mx-1 md:mx-0 md:px-0">
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<i
class="ri-star-line text-orange-200 absolute text-2xl left-0 ml-1 rotate-90"></i>
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/肖宾简历/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
肖宾简历
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-06-18</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
基本信息
姓名: 肖宾 | 性别: 男
联系电话: 185-7164-xxxx | 邮箱: xiaobin-phd@gmail.com
教育背景
华中农业大学（211） 水产动物医学 | 硕...
</div>
<a href="https://xiaobin-phd.github.io/post/肖宾简历/" class="btn">
Read more
</a>
</div>
<img
class="flex-shrink-0 self-start md:ml-4 mb-4 md:mb-0 rounded-sm object-cover featured-img order-1 md:order-2 w-full h-40 md:w-56 md:h-32"
loading="lazy"
src="https://xiaobin-phd.github.io/post-images/肖宾简历.jpg"
alt="肖宾简历" />
</div>
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/1102-hui-yi-zong-jie/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
1102会议总结
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-11-03</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
1、会议概括
近期，实验室出现了工作态度不积极、工作执行不到位、个人奋斗意识不强以及试剂耗材浪费等问题。对此，申老师对实验室成员进行了批评，并明确提出了整改意见。要求各位成员积极开展自查自纠，务必采取有效措施，切实改变当前状况，以提升实验室...
</div>
<a href="https://xiaobin-phd.github.io/post/1102-hui-yi-zong-jie/" class="btn">
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</a>
</div>
</div>
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/dai-xie-shu-ju-ku-tuo-zhan/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
代谢数据库拓展
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-09-17</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
代谢相关数据库拓展
目前已完成了初步注释，使用eggnog数据库，得到3964条基因（带有EC号）。
后续工作分为两个步骤：1. 对初步结果进行手动验证，有的基因可能与代谢关系不那么直接，可适当删除。2. 查阅文献，拓展数据库进行注释，与初...
</div>
<a href="https://xiaobin-phd.github.io/post/dai-xie-shu-ju-ku-tuo-zhan/" class="btn">
Read more
</a>
</div>
</div>
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/zhu-dai-xie-xiang-guan-ji-yin-zhu-shi/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
猪代谢相关基因注释
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-09-09</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
1、参考基因组下载
基因组选择：Genome assembly Sscrofa11.1 （官方参考基因组，杜洛克雌猪）
wget -c https://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/003...
</div>
<a href="https://xiaobin-phd.github.io/post/zhu-dai-xie-xiang-guan-ji-yin-zhu-shi/" class="btn">
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</a>
</div>
</div>
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/20240831-bosstalk/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
20240831-BossTalk
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-08-31</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
前天半夜接收了boss的文献，加急阅读后，今天与之探讨。内容主要为后续开展的研究方向，整体和之前所定的不变，大方向还是探究弓形虫和宿主的代谢互作机制，阐明寄生虫依赖的核心代谢通路，探索寄生虫为什么要”寄生“。在此基础上进行了细化，分为两条路...
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</a>
</div>
</div>
<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/shi-yan-xiang-guan-gai-nian-qanda/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
实验相关概念Q&A
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-06-20</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
1、染色质重塑因子
染色质重塑因子（chromatin remodeling factors）是调控染色质结构和基因表达的重要蛋白质复合物。它们通过改变核小体（由DNA缠绕组装的结构）的位置、构象或组成，来调控基因的转录、复制、修复等过程。...
</div>
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<div
class="p-8 border-b border-gray-200 dark:border-gray-700 flex relative overflow-hidden flex-col md:flex-row animated fadeIn">
<div class="flex-1 order-2 md:order-1">
<h2 class="text-2xl font-semibold mb-4">
<a
href="https://xiaobin-phd.github.io/post/a-brief-compasison-of-gsmms-reconstruction/"
class="text-gray-700 dark:text-gray-200 border-b-2 border-dotted border-gray-200 dark:border-gray-400 dark:hover:border-gray-200 hover:border-gray-600 transition-all duration-100">
A brief compasison of GSMMs reconstruction
</a>
</h2>
<div class="mb-4 text-xs text-gray-500">2024-06-18</div>
<div class="mb-4 text-gray-500 dark:text-gray-300">
1. AuReMe (Automatic Reconstruction of Metabolic Models，2018)
# Description
good traceability of the whole reconstructio...
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